Directory Profile

Peter Wipf, PhD

Office: 1301 Chevron Building

Phone: 412-624-8606


Assistant Professor (9/90-8/95), Associate Professor (9/95-1/97), Professor (2/97-6/04), Distinguished
University Professor of Chemistry (7/04-present), all at University of Pittsburgh • Director, Centers for
Combinatorial Chemistry and Chemical Methodologies & Library Development, University of Pittsburgh (12/97-present) • Professor of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh (11/01-present) • Adjunct Professor (2002-present), Duke University, Department of Chemistry.

Ernest Guenther Award in the Chemistry of Natural Products (2009) • Chancellor’s Distinguished Research Award (2008) • Fellow of the Royal Society of Chemistry (FRSC, 2004) • ISHC Katritzky Award in Heterocyclic Chemistry (2003) • Fellow of the AAAS (2002) • Chair, Gordon Research Conference on Stereochemistry (June 9-14, 2002) • Novartis Research Award (2000, 2001) • Japan Society for the Promotion of Science Fellow (2000) • Akron Section ACS Award (1998) • Arthur C. Cope Scholar Award (1998) • Merck Young Investigator Award (1995) • Zeneca Award for Excellence in Chemistry (1995) • Camille Dreyfus Teacher-Scholar Award (1995) • American Cancer Society Junior Faculty Research Award (1995-1998) • NSF Presidential Faculty Fellow (1994-1999) • ETH Ruzicka Award (1994) • Alfred P. Sloan Research Fellow (1994-1996) • Eli Lilly Grantee (1993-1995).

Board of Editors of Organic Syntheses, Inc. • Board of Directors, Organic Reactions, Inc. • Series Editor, The
Chemistry of Heterocyclic Compounds, J. Wiley

Total synthesis of natural products, organometallic methodology, and medicinal chemistry.

- "Mutations in the Phosphatidylinositol-3-kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras is a Sominant Predictor for Resistance." Ihle, N. T.; Lemos, R.; Wipf, P.; Yacoub, A.; Mitchell, C.; Siwak, D.; Mills, G. B.; Dent, P.; Kirkpatrick, D. L.; Powis, G. Cancer Res. 2009, 69, 143-150.
- "A Microwave Assisted Intramolecular-Furan-Diels-Alder Approach to 4-Substituted Indoles." Petronijevic, F.; Timmons, C.; Cuzzupe, A.; Wipf, P. Chem. Commun. 2009, (1), 104-106.
-"Triple Hybrids of Steroids, Spiroketals, and Oligopeptides as New Biomolecular Chimeras." Banerjee, A.; Sergienko, E.; Vasile, S.; Gupta, V.; Vuori, K.; Wipf, P. Org. Lett. 2009, 11(1), 65-68.
- "Potent and Selective Disruption of Protein Kinase D Functionality by a Benzoxoloazepinolone." Sharlow, E. R.; Giridhar, K. V.; LaValle, C. R.; Chen, J.; Leimgruber, S.; Barrett, R.; Bravo-Altamirano, K.; Wipf, P.; Lazo, John S.; Wang, Q. J. J. Biol. Chem. 2008, 283(48), 33516-33526.
-"Rhodium(I)-Catalyzed Cycloisomerizations of Bicyclobutanes." Walczak, M. A. A.; Wipf, P. J. Am. Chem. Soc. 2008, 130(22), 6924-6925.
- "A Mitochondria-Targeted Nitroxide/Hemigramicidin S Conjugate Protects Mouse Embryonic Cells Against Gamma Irradiation." Jiang, J.; Belikova, N.; Hoye, A. T.; Zhao, Q.; Epperly, M. W.; Greenberger, J. S.; Wipf, P.; Kagan, V. E. Int. J. Radiat. Oncol. Biol. Phys. 2008, 70(3), 816-825.
- "Targeting Mitochondria." Hoye, A. T.; Davoren, J.; Wipf, P.; Fink, M. P.; Kagan, V. E. Acc. Chem. Res. 2008, 41(1), 87?97.
- "Pyrimidinone-Peptoid Hybrid Molecules with Distinct Effects on Molecular Chaperone Function and Breast Cancer Cell Proliferation." Wright, C. M.; Chovatiya, R. J.; Jameson, N. E.; Turner, D. M.; Zhu, G.; Werner, S.; Huryn, D. M.; Pipas, J. M.; Day, B. W.; Wipf, P.; Brodsky, J. L. Bioorg. Med. Chem. 2008, 16, 3291-3301.