Office: VAPHS, 7180 Highland Drive

Phone: 412-360-6781

Fax: 412-365-5917


Jeffrey Yao is a Research Professor of Psychiatry at the University of Pittsburgh School of Medicine with secondary appointment in the Department of Pharmaceutical Sciences at the University of Pittsburgh School of Pharmacy, and Senior Research Career Scientist and Director of Neurochemistry and Psychopharmacology Laboratory at the VA Pittsburgh Healthcare System (Highland Drive).

He received a B.S. in Chemistry from Fu-Jen Catholic University (Taipei, Taiwan), earned his Ph.D. degree in Biological Chemistry from the University of Detroit, and received postdoctoral training in Lipid Chemistry at the University of Michigan.

He was a member of Peripheral Nerve Research Center at Mayo Clinic before moving to Pittsburgh and has been a faculty member at the University of Pittsburgh since 1985. His research interest primarily focuses on the biochemical aspects of disease processes that are related to mental illness and neurological disorders.

Application of metabolomics in psychosis and therapeutic monitoring.

Yao, J.K., Wengenack, T.M., and Poduslo, J.F. (2009) Reduced Membrane Lipids in the Cortex of Alzheimer's Disease Transgenic Mice. Neurochemical Research 34:102-108.

Thomas, E.A., Yao, J.K. (2007) Clozapine specifically alters the arachidonic acid pathway in mice lacking apolipoprotein D. Schizophr Res 89:147-153.

Reddy, R.D., Keshavan, M.S. Yao, J.K. (2007) Blunted serotonergic responsivity in platelets from neuroleptic-naive patients at first episode of schizophrenia. Schizophr Res 90:81-85.

Yao, J.K., Leonard, S., Reddy, R.D. (2006) Altered glutathione redox state in schizophrenia. Disease Markers 22:83-93.

Yao, J.K., and Reddy, R.D. (2005) Metabolic investigation in psychiatric disorders. Molecular Neurobiology 31:193-203.

Yao, J.K., and van Kammen, D.P. (2004) Membrane phospholipids and cytokine interaction in schizophrenia. Int. Rev. Neurobiol. 59: 297-326.

Senior Research Career Scientist Award
Department of Veterans Affairs
Jeffrey K. Yao

Application of Metabolomics in Psychosis and Therapeutic Monitoring Department of Veterans Affairs
Jeffrey K. Yao and Billy Day

Determination of Plasma Fatty Acids Distribution in Healthy Volunteers
National Heart, Lung, and Blood Institute
Jeffrey K. Yao and Matthew F. Muldoon

Determination of Monoamine Metabolites in CSF, Plasma, and Urine of Patients with Subarachnoid Hemorrhage
National Institute of Nursing Research
Jeffrey K. Yao, Samuel Poloyac, and Leslie Hoffman