Directory Profile

Program: PhD
Track: Clinical Pharmaceutical Sciences
Advisor: Thomas D. Nolin, PharmD, PhD

Morgan Casal is a PhD student in the Clinical Pharmaceutical Scientist Program in Dr. Tom Nolin's lab. Her research interests include physiologically-based pharmacokinetic modeling, changes in nonrenal clearance in patients with kidney impairment, and the implications of different evaluations of kidney function on clinical and regulatory decision-making.

Morgan received her Doctor of Pharmacy (PharmD) degree from the University of Pittsburgh School of Pharmacy with an Area of Concentration in Research in 2019 and is a registered pharmacist in Pennsylvania.

PUBLICATIONS

1. Casal MA, Nolin TD, Beumer JH. Estimation of Kidney Function in Oncology: Implications for Anticancer Drug Selection and Dosing. Clin J Am Soc Nephrol. 2019 Apr 5;14(4):587-595. PMID: 30890575.

2. Cherian MT, Chai SC, Wright WC, Singh A, Casal MA, Zheng J, Wu J, Lee RE, Griffin PR, Chen T. CINPA1 binds directly to constitutive androstane receptor and inhibits its activity. Biochem Pharmacol. 2018 Jun;152:211-223. PMID: 29608908.

3. Böhm S, Mihalevic MJ, Casal MA, Bernstein KA. Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells. DNA Repair (Amst). 2015 Feb;26:1-14. PMID: 25588990.


ELECTRONIC PUBLICATIONS

1. Casal MA. "Veverimer: A Promising Investigational Agent for Long-Term Treatment of Metabolic Acidosis in Chronic Kidney Disease." Pharmacotherapy Updates, 9 October 2019. McGraw-Hill, New York, NY, 2019. AccessPharmacy. http://accesspharmacy.mhmedical.com

2. Flanigan JA, Casal MA. "Beneficial Cardiorenal Effects of SGLT2 Inhibitors." Pharmacotherapy Updates, 13 May 2019. McGraw-Hill, New York, NY, 2019. AccessPharmacy. http://accesspharmacy.mhmedical.com

3. Casal MA, Nolin TD. "Nephrotoxic Potential of Novel Anticancer Immunotherapies." Pharmacotherapy Updates, 13 August 2018. McGraw-Hill, New York, NY, 2018. AccessPharmacy. http://accesspharmacy.mhmedical.com

4. Casal MA, Nolin TD. "Impact of Electronic Alerts on Detection and Course of Acute Kidney Injury." Pharmacotherapy Updates, 21 May 2018. McGraw-Hill, New York, NY, 2018. AccessPharmacy. http://accesspharmacy.mhmedical.com

5. Casal MA, Nolin TD. "Anticoagulation in Older Patients with Atrial Fibrillation and Chronic Kidney Disease." Pharmacotherapy Updates, 21 May 2018. McGraw-Hill, New York, NY, 2018. AccessPharmacy. http://accesspharmacy.mhmedical.com

6. Casal MA, Nolin TD. “N-acetylcysteine and Sodium Bicarbonate for Prevention of Contrast Media-Induced Nephrotoxicity.” Pharmacotherapy Updates, 27 December 2017. Access Pharmacy. McGraw-Hill, New York, NY, 2017. AccessPharmacy. http://accesspharmacy.mhmedical.com