Topics in translational research (PHARM 3034)

This course is structured as a journal club focused on translational investigations for graduate students with interests in clinical and translational research within the pharmaceutical sciences. This course will be offered as an interactive video conference journal discussion with students from the University of Minnesota and the University of North Carolina. Articles emphasizing methods which allow for translation from preclinical to clinical investigation will be discussed in several different therapeutic areas with emphasis on pharmacometrics, genomics, biomarker validation, and drug discovery.


Describe the current state of knowledge about a biomedical, clinical, or public health problem.

Critique clinical and scientific evidence derived from literature.

Interpret primary research literature within the pharmaceutical sciences.

Extract literature from appropriate bibliographic sources.

Identify important outcome measures for incorporation into patient oriented clinical trial design.

Identify barriers in translating research discoveries into meaningful changes in human health.

Evaluate possible problems in the design and execution of a study in the pharmaceutical sciences.

Apply fundamental principles of statistical analysis, such as power analysis, correlation, causation, regression, and summary statistics.

Assess the clinical implications of scientific information.

Develop presentations describing proposed research, research in progress, or research findings.

Demonstrate professionalism, interpersonal skills and collegial approaches to teamwork.

* Highlight denotes properties specific to the Clinical Pharmaceutical Sciences track.