Edward Horn, PharmD, BCCCP, joined the Department of Pharmacy and Therapeutics at the School of Pharmacy in July 2018 and holds the title of Associate Professor. He also serves as a clinical pharmacy Specialist in heart transplantation and mechanical circulatory support with the University of Pittsburgh Medical Center Heart and Vascular Institute. He received his Doctor of Pharmacy degree from the University of Pittsburgh in 2000, with subsequent post-graduate training. Horn completed his PGY-1 Pharmacy Practice Residency at Thomas Jefferson University Hospital in Philadelphia, Pennsylvania. Upon completion, he returned to the University of Pittsburgh for his PGY-2 Specialty Residency in Critical Care Pharmacy Practice.
From 2002-2007, Horn was a clinical pharmacy specialist in Trauma/Surgical Critical Care at the Johns Hopkins Hospital in Baltimore, Maryland. During that time, he aided in the care of the critically ill and was active in both student and resident precepting, as well as clinical research. He then joined the pharmacy department at Allegheny General Hospital in Pittsburgh in 2007 as a clinical pharmacy specialist in cardiothoracic surgery with key roles in the in the cardiothoracic surgery ICU, heart transplant, and mechanical circulatory support programs there. He also served as the critical care pharmacy residency program director there from 2012 to 2018.
Horn's current clinical practice sites include the heart transplant clinic as well as the heart transplant/mechanical support service at UPMC. His clinical research interests surround improving the long-term care of both heart transplant recipients and patients with durable mechanical support devices, including immunosuppression management and anticoagulant/antiplatelet monitoring in mechanical circulatory support.
APPE Preceptor of the Year, University of Pittsburgh School of Pharmacy 2021-2022
Pharmacotherapy of sepsis.
Pavlik DJ, Simpson RW, Horn ET, King L, Finoli L.
Crit Care Nurs Q. 2015 Apr-Jun;38(2):121-36. doi: 10.1097/CNQ.0000000000000053.
PMID: 25741953 Review.
Apixaban as an alternative to warfarin for patients with a left ventricular assist device.
Horn ET, Baker E, Dolphin J, Mitchell M, Modany A, Shullo MA, Coons JC.
Am J Health Syst Pharm. 2022 May 24;79(11):826-829. doi: 10.1093/ajhp/zxac028.
PMID: 35088839 No abstract available.
Primary Graft Dysfunction in Heart Transplant Recipients-Risk Factors and Longitudinal Outcomes.
Smith NF, Salehi Omran S, Genuardi MV, Horn ET, Kilic A, Sciortino CM, Keebler ME, Kormos RL, Hickey GW.
ASAIO J. 2022 Mar 1;68(3):394-401. doi: 10.1097/MAT.0000000000001469.
PMID: 34593684
Outcomes of systemic anticoagulation with bivalirudin for Impella 5.0.
Fabrizio C, Levito MN, Rivosecchi R, Bashline M, Slocum B, Kilic A, Toma C, Murray H, Ramanan R, Fowler J, Hickey GW, Horn ET.
Int J Artif Organs. 2021 Oct;44(10):681-686. doi: 10.1177/03913988211032238. Epub 2021 Jul 12.
PMID: 34250827
Safe use of hemodialysis for dabigatran removal before cardiac surgery.
Wanek MR, Horn ET, Elapavaluru S, Baroody SC, Sokos G.
Ann Pharmacother. 2012 Sep;46(9):e21. doi: 10.1345/aph.1R081. Epub 2012 Aug 7.
PMID: 22872748
Assessing Anticoagulation Practice Patterns in Patients on Durable Mechanical Circulatory Support Devices: An International Survey.
Jennings DL, Horn ET, Lyster H, Panos AL, Teuteberg JJ, Lehmkuhl HB, Perez A, Shullo MA.
ASAIO J. 2016 Jan-Feb;62(1):28-32. doi: 10.1097/MAT.0000000000000274.
PMID: 26309097
Outcomes of systemic bivalirudin and sodium bicarbonate purge solution for Impella 5.5.
Bashline M, DiBridge J, Klass WJ, Morelli B, Kaczorowski D, Schmidhofer M, Horn ET, Gomez H, Ramanan R, Hickey GW, Rivosecchi RM.
Artif Organs. 2023 Feb;47(2):361-369. doi: 10.1111/aor.14428. Epub 2022 Oct 31.
PMID: 36271639
Bloodstream Infections in Continuous Flow Left Ventricular Assist Device Recipients: Diagnostic and Clinical Implications.
Kyvernitakis A, Pappas O, Farmakiotis D, Horn ET, Benza RL, Bailey SH, Agarwal R.
ASAIO J. 2019 Nov/Dec;65(8):798-805. doi: 10.1097/MAT.0000000000000881.
PMID: 30234503
Basiliximab induction versus no induction in adult heart transplantation.
Rudzik KN, Rivosecchi RM, Palmer BA, Hickey GW, Huston JH, Keebler ME, Kaczorowski DJ, Horn ET.
Clin Transplant. 2023 Feb 15:e14937. doi: 10.1111/ctr.14937. Online ahead of print.
PMID: 36793206
The pathophysiology of endothelin in complications after solid organ transplantation: a potential novel therapeutic role for endothelin receptor antagonists.
Raina A, Horn ET, Benza RL.
Transplantation. 2012 Nov 15;94(9):885-93. doi: 10.1097/TP.0b013e31825f0fbe.
PMID: 23037008 Review.
Impact of carfilzomib-based desensitization on heart transplantation of sensitized candidates.
Sriwattanakomen R, Xu Q, Demehin M, Shullo MA, Mangiola M, Hickey GW, Sciortino CM, Horn ET, Keebler ME, Zeevi A.
J Heart Lung Transplant. 2021 Jul;40(7):595-603. doi: 10.1016/j.healun.2021.03.001. Epub 2021 Mar 5.
PMID: 33785250
Erythropoietic Agents for Anemia of Critical Illness
Shermock KM, Horn E, Rice TL
American Journal of Health System Pharmacy 2008;65(6):540-546
Number Needed to Treat and Cost of Recombinant Human Erythropoietin to Avoid One Transfusion Related Adverse Event in Critically Ill Patients
Shermock KM, Horn E, Lipsett PA, Pronovost PJ, Dorman T.
Critical Care Medicine, 2005:33(3):497-503
Yunis AA, Hickey GW, Thoma F, Sezer A, Horn ET, Keebler M, Mulukutla SR, Sciortino C.
Presented at the International Society for Heart and Lung Transplantation 2020 Annual Meeting
Montreal, Quebec, Canada
April 22-25, 2020
Carfilzomib for Heart Transplant Desensitization
Sriwattanakomen R, Xu Q, Zeevi A, Shullo MA, Keebler ME, Mangiola M, Hickey GW, Sciortino CM, Horn ET.
Presented at the International Society for Heart and Lung Transplantation 2020 Annual Meeting
Montreal, Quebec, Canada
April 22-25, 2020
Should mTOR Inhibitors Have a Prominent Role in Immunosuppression After Heart Transplantation? Pro viewpoint
Presented at The American College of Clinical Pharmacy Annual Meeting
New York, New York
October 26-29, 2019
Looking Back and Moving Forward – Immunosuppression Before and After Cancer
Presented at The International Society for Heart and Lung Transplantation 2018 Annual Meeting
Nice, France
April 11-14, 2018
Bloodstream Infections in Left Ventricular Assist Device Recipients Awaiting Transplantation
Kyvernitakis A, Pappas O, Farmakiotis D, Horn ET, Benza RL, Bailey SH, Agarwal R.
Presented as an oral presentation
Presented at The International Society for Heart and Lung Transplantation 2018 Annual Meeting,
Nice, France
April 11-14, 2018
Prevention of Thrombosis in Mechanical Support: Where Are We Going?
Presented at International Society of Heart and Lung Transplant 2017
Annual Meeting
San Diego, California
April 5-8, 2017
Evaluation of Prothrombin Complex Concentrate in Warfarin Reversal Prior to Heart Transplantation in Patients with Durable Mechanical Circulatory Support.
Konopka CI, Horn ET, Murali S, Benza RL, Moraca RJ, Bailey SH.
Presented as an oral presentation
Presented at International Society of Heart and Lung Transplant 2017
Annual Meeting
San Diego, California
April 5-8, 2017
