Pharmacometrics and Systems Pharmacology Specialization


The Pharmacometrics and Systems Pharmacology program focuses on applying Pharmacometrics and system pharmacology techniques to facilitate the development of novel drug candidates that are less likely to fail during clinical trials and to provide a better understanding of drug mechanisms of action and therapeutic effects at the systems pharmacology level.

  • You will develop a broad knowledge of pharmacometrics and systems pharmacology to develop drug candidates that are less likely to fail during clinical trials.
  • You will develop strong computational modeling and simulation expertise from drug target fishing, to drug lead identification, to drug profile optimization.
  • You will develop strong computational expertise on pharmacokinetics (PK) and pharmacodynamics (PD) modeling and simulation.
  • You will develop skills on multiscale modeling of biological processes at the molecular, gene, organ and organism levels.
  • Your will have opportunities to study with faculty from a variety of background including computer-aided drug design, computational and systems biology/pharmacology, population PK/PD modeling, computational chemical genomics, computational biophysics, etc.
  • Candidates with programming experience, basic/intermediate knowledge in statistics and/or hands-on modeling experience are highly desired.

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Year 1 Fall

Course Number Course Name Credits
PHARM 3068/PHARM 3069 Systems Pharmacology / Pharmacometrics 3
PHARM 3028 Pharmacology and Therapeutics 4
PHARM 3040 Statistical Methods 3
TBD Python Programming 2
PHARM 3024 Seminar 1
PHARM 3048/3009/3000/3036 Journal Club 0-5
PHARM 3042 Research Practicum 1
Electives   0-6

Year 1 Spring

Course Number Course Name Credits
PHARM 3023 Foundation in Pharm. Sci. 5
PHARM 3048/3009/3000/3027 Journal Club 1-2
PHARM 3024 Pharmaceutical Sciences Seminar 1
PHARM 3042 Research Practicum 0-6
Elective 0-6

Year 2 Fall

Course Number Course Name Credits
PHARM 3069/PHARM 3068 Pharmacometrics / Systems Pharmacology 3
PHARM 3048/3009/3000/3036 Journal Club 1
PHARM 3024 Pharmaceutical Sciences Seminar 1
PHARM 3042 Research Practicum 0-5
Elective 0-6

Year 2 Spring

Course Number Course Name Credits
PHARM 3048/3009/3000/3036 Journal Club 1
PHARM 3024 Pharmaceutical Sciences Seminar 1
PHARM 2010 Master of Science Thesis 1-9
Elective 0-6

Primary Contact

Dr. Xiang-Qun Xie

Associate Dean and Professor of School of Pharmacy, Director of CCGS and CDAR centers.

412-624-6053

XieXQsean@pitt.edu