Professor Raman Venkataramanan, PhD, Assistant Professor Christopher Ensor, PharmD, BCPS,Transplant Pharmacy Fellow Cody Moore, PharmD, BCPS, and PhD Candidate Rujuta Joshi, BS, are the recipients of a 2-year research grant awarded by the University of Pittsburgh Cancer Institute - Institute for Precision Medicine.
Their research will focus on precision guided dosing of mycophenolate mofetil in lung transplantation. Mycophenolate mofetil is not routinely monitored among lung transplant recipients due to the duration of blood sampling and cost. The molecular target of mycophenolate mofetil is inosine 5'-monophosphate dehydrogenase (IMPDH). The objective of the study is to improve clinical outcomes in lung transplant recipients by using an IMPDH-guided approach to mycophenolate mofetil dosing in lung transplant recipients.
