PittPharmacy faculty member Xiaochao Ma, PhD was awarded a grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) for his project Mechanisms of Adverse Effects of Anti-tuberculosis Drugs.
Rifampicin and isoniazid co-therapy frequently causes liver injury, and even liver failure. This proposed project will provide a novel mechanistic understanding of the liver injury induced by rifampicin and isoniazid co-therapy, which can be applied to predict, prevent, and treat this toxic event.
Xiaochao Ma is an associate professor at the School of Pharmacy in the pharmaceutical sciences department.