Venkat’s research focuses on optimizing drug therapy in pregnancy “prevention of preterm labor by optimizing the use of 17-hydroxyprogesterone caproate during pregnancy and Optimizing buprenorphine treatment in pregnancy”; and “optimization of use of medications in organ transplant patients”. Consistently NIH funded for OBGYN pharmacology work for the past 20years.
Biosketch:
Raman Venkataramanan, Ph.D; FCP; FAAPS
Distinguished Service Professor of Pharmaceutical sciences and Pathology, University of Pittsburgh.
Director of clinical pharmacokinetics laboratory
Director of Therapeutic Drug Monitoring and Toxicology, UPMC
Interim Director of CPPF, HCC, UPMC
Pharmacy degree from University of Madras, India
Master of pharmacy from Birla Institute of Technology and Science, India;
Doctorate from University of British Columbia, Canada.
Postdoctoral fellowship at the University of Washington
Faculty University of Pittsburgh since 1980.
Editorial board member for Therapeutic Drug Monitoring, and four online journals.
Editor for the American Journal of Analytical Chemistry.
Reviewer for 10 additional journals
Presented more than 200 lectures/seminars at national/international meetings
Published over 450 papers in peer reviewed journals
Mentored 39 Ph.Ds; 10 MS; 30 Fellows; 10 Faculty
Member in AAPS, ACCP, IATDMCT, ITS and AST.
Residency:
Solid Organ Transplant
Resident Position:
Preceptor
- Ph.D.
Education & Training
Clinical Pharmaceutical Sciences
Drug Formulations and Delivery
Drug Abuse and Prevention
Pharmacogenetics
Distinguished Alumni Award – BITS Pilani 2024
Distinguished Investigator – ACCP 2024
Distinguished Service Professor – University of Pittsburgh 2023-2024
University of Pittsburgh Rho Chi Society Award “Outstanding scholarly Contribution award" 2022
HiREC Visiting Endowed Chair at the University of PuertaRico 2021
AAPS Distinguished Service Award 2021
Graduate Faculty of the year University of Pittsburgh School of Pharmacy 2022
Distinguished Scientist Award AAiPS 2016
Graduate Faculty of the Year Award 2015
Honored/invited speaker at Agents for change Symposium organized by the 2014 University of British Columbia Vancouver Canada
APhA Tyler Award for Stimulation of Research 2011
University of Pittsburgh- Provost’s Award for Excellence in Mentoring 2009
University of Pittsburgh Rho Chi Society Award “Innovations in Teaching award” 2009
ACCP-BMS Award for Mentoring in Clinical Pharmacology 2009
University of Pittsburgh Rho Chi Society Award “Outstanding scholarly contribution award" 2007
Ranbaxy Research Award in Pharmaceutical Sciences 1997-1998 1998 (Awarded by Ranbaxy Limited India)
Distinguished Research Scientist Award. The Institute of Kidney Diseases and Research center and the Institute of Transplantation, Ahmadabad, India 1998
Fellow of the American Association of Pharmaceutical Scientists 1996
Visiting Scientist, K.J. Hospital, Madras, India (5-month period) 1994 – 1995
Orator – SLANT - First scientific session of the Sri Lanka Association of Nephrology and Transplantation 1995
Medical Research Council, Canada - Special Visiting Scientist 1990 University of British Columbia, Vancouver, BC Canada
Fellow of the American College of Clinical Pharmacology 1989 – Present
Alberta Heritage Foundation - Visiting Scientist
University of Alberta at Edmonton, Alberta, Canada 1985
Canadian Heart Foundation Fellowship, Canadian Heart Foundation, PhD 1978 – 1979
British Columbia Heart Foundation Fellowship, British Columbia Heart Foundation1977 – 1978
U.B.C. Graduate Fellowship, U.B.C., PhD 1975 – 1977
Summer Session Research Scholarship, U.B.C., Master of Pharmacy 1975
Graduate Student Teaching Assistantship, U.B.C., Master of Pharmacy, PhD 1974 – 1975
Stanley Drug Products Novo Group Scholarship, Master of Pharmacy 1974 – 1975
University Grants Commission Junior Fellowship, Master of Pharmacy 1972 – 1974
Bashyam Memorial Prize for Best Outgoing Pharmacy Student, University of Madras, B. Pharm 1972
National Merit Scholarship, Government of India, During Pre University and Bachelor of Pharmacy 1967 – 1972
Best Outgoing Student, SRM High School, Madras, S.S.L.C. 1967
1. Venkataramanan, R. "Drug Action Planar Aspects". J Pharm Soc Pilani 12:27 29 (1974).
2. Venkataramanan, R. and Axelson, J.E. "An Electron Capture Detector Gas Chromatographic Technique for the Estimation of Tocainide in Biological Fluids". J Pharm Sci. 67:201 205 (1978).
3. Venkataramanan, R. and Axelson, J.E. "Dose Dependent Pharmacokinetics of Tocainide in the Rat". J Pharmacol Exp. Ther 215:231 234 (1980).
4. Venkataramanan, R. and Axelson, J.E. "The Effect of Phenobarbital and SKF 525A on Tocainide in the Rat". J Pharmacol Exp Ther 215:235 239 (1980).
5. Venkataramanan, R. and Axelson, J.E. "3 (2,6 xylyl) 5 Methyl Hydantoin A Metabolite or a Metabonate of Tocainide in Rats?" Xenobiotica 11:259 265 (1981).
6. Venkataramanan, R. and Axelson, M. "Metabolism of Tocainide in the Rat". J Pharm Sci 71:491 494 (1982).
7. Patel, I.H., Venkataramanan, R., Levy, R.H., Vishwanathan, C.T. and Ojermann, L.M. "Diurnal Oscillations in the Plasma Protein Binding of Valproic Acid and Phenytoin". Epilepsia 23:283 290 (1982).
8. Kunka, R.L., Venkataramanan, R., Stern, R.M. and Ladik, C.F. "Excretion of Propoxyphene and Norpropoxyphene into Breast Milk". Clin Pharmacol Ther 35:675 680 (1984).
9. Venkataramanan, R., Ptachcinski, R.J., Burckart, G.J., Yang, S.L., Starzl, T.E. and Van Thiel, D.H. "The Clearance of Cyclosporine by Hemodialysis". J Clin Pharmacol 24:528 531 (1984).
10. Burckart, G.J., Venkataramanan, R. and Ptachcinski, R.J. "Response to Usefulness of Cyclosporine Monitoring Questioned" Letter. Clin Pharmacy 3:243 (1984).
11. Ptachcinski, R.J., Venkataramanan, R. and Burckart, G.J. "Cyclospor¬ine A Review". Drug Intel Clin Pharm 19:90 100 (1985).
12. Venkataramanan, R., Ptachcinski, R.J., Burckart, G.J., Yang, S.L. and Starzl, T.E. "Extraction Ratio of Cyclosporine". J Pharm Sci 74:901 902 (1985).
13. Howrie, D.L., Ptachcinski, R.J., Griffith, B., Hardesty, R.L., Rosenthal, J.T., Burckart, G.J. and Venkataramanan, R. "Cyclosporine Associated Anaphylactoid Reactions: Possible Role of Cremophor EL". Drug Intel Clin Pharm 19:425 427 (1985).
14. Venkataramanan, R., Starzl, T.E., Yang, S., Burckart, G.J., Ptachcinski, R.J., Shaw, B.W., Iwatsuki, S., Van Thiel, D.H., Sanghvi, A. and Seltman, H. "Biliary Excretion of Cyclosporine in Liver Transplant Patients". Transplant Proc 27:286 289 (1985).
15. Burckart, G.J., Starzl, T., Williams, L., Sanghvi, A., Gartner, C., Venkataramanan, R., Zitelli, B., Malatack, J., Urbach, A., Diven, W., Ptachcinski, R., Shaw, B. and Iwatsuki, S. "Cyclosporine Monitoring and Pharmacokinetics in Pediatric Liver Transplant Patients". Transplant Proc 27:1172 1175 (1985).
16. Ptachcinski, R.J., Venkataramanan, R., Rosenthal, J.T., Taylor, R.J. and Hakala, T.R. "The Effect of Food on the Absorption of Cyclosporine". Transplant 40:174 176 (1985).
17. Ptachcinski, R.J., Gray, J., Venkataramanan, R., Burckart, G.J., Van Thiel, D.H. and Rosenthal, J.T. "Cyclosporine Associated Anaphylaxis Additional Precautions". Lancet 1:636 637 (1985).
18. Ptachcinski, R.J., Venkataramanan, R., Rosenthal, J.T., Burckart, G.J., Taylor, R. and Hakala, T. "Cyclosporine Pharmacokinetics in Renal Transplant Patients”. Clin Pharmacol Ther 38:296 300 (1985).
19. Burckart G, Venkataramanan, R, Ptachcinski R. Cyclosporine Monitoring. American Association of Clinical Chemistry. 6: 1-11, 1985.
20. Stoehr, G.P., Venkataramanan, R. and Dauber, J.H. "Comparison of Methods for Determining Unbound Theophylline Concentrations". Therap Drug Mon 8:42-46 (1986).
21. Ptachcinski, R.J., Venkataramanan, R. and Burckart, G.J. "The Clinical Pharmacokinetics of Cyclosporine". Clin Pharmacokin 11:107 132 (1986).
22. Ptachcinski, R.J., Hakala, T.R., Schleicher, C., Rosenthal, J.T., Taylor, R.J., Carpenter, B., Burckart, G.J., Venkataramanan, R. and Zheng, S. "Cyclosporine (CyA) in Cadaveric Renal Transplantation: Analysis of Three Administration Regimens". Transplant Proc 18: 789 790 (1986).
23. Ptachcinski, R.J., Burckart, G.J., Rosenthal, J.T., Venkataramanan, R., Howrie, D.L., Taylor, R.J., Avner, E.D., Ellis, D. and Hakala, T.R. "Cyclosporine (CyA) Pharmacokinetics in Children Following Cadaveric Renal Transplantation". Transplant Proc 18: 766 767 (1986).
24. Zaghloul, I., Burckart, G.J., Starzl, T.E., Todo, S., Ptachcinski, R.J. and Venkataramanan, R. "Cyclosporine G Analysis and Monitoring by High Pressure Liquid Chromatography". Transplant Proc 18: 771 773 (1986).
25. Venkataramanan, R., Burckart, G.J., Ptachcinski, R.J., Lee, A., Hardesty, R.L. and Griffith, B.P. "Cyclosporine Pharmacokinetics in Heart Transplant Patients". Transplant Proc 18: 768 770 (1986).
26. Todo, S., Porter, K.A., Kam, I., Lynch, S., Venkataramanan, R., DeWolf, A. and Starzl, T.E. "Canine Liver Transplantation under Nva2 Cyclosporine versus Cyclosporine". Transplant 41:296 300 (1986).
27. Huang, M.L., Burckart, G.J. and Venkataramanan, R. "Sensitive high-performance Liquid Chromatographic Analysis of Vitamin E and Vitamin A Using Amperometric and Ultraviolet Detection". J. Chrom 380: 331 338 (1986).
28. Mehta, M.U., Venkataramanan, R., Burckart, G.J., Ptachcinski, R.J., Yang, S.L., Gray, J.A., and Van Thiel, D.H. "Antipyrine Kinetics in Liver Disease and Transplantation". Clin Pharmacol Therap 39:372 377 (1986).
29. Ptachcinski, R.J., Logue, L.W., Burckart, G.J. and Venkataramanan, R. "Stability and Availability of Cyclosporine 5% Dextrose Injection or 0.9% Sodium Chloride Injection". Am J Hosp Pharm 43:94 97 (1986).
30. Venkataramanan, R., Yang, S., Burckart, G.J., Ptachcinski, R.J., Van Thiel, D.H. and Starzl, T.E. "Diurnal Variation in Cyclosporine Kinetics". Therap Drug Monit 8: 380 381 (1986).
31. Burckart, G.J., Venkataramanan, R., Ptachcinski, R.J., Starzl, T.E., Gartner, C.J., Zitelli, B.J., Malatack, J.J., Shaw, B.W., Iwatsuki, S. and Van Thiel, D.H. "Cyclosporine Absorption following Orthotopic Liver Transplantation". J Clin Pharmacol 26:647 651 (1986).
32. Ptachcinski, R.J., Carpenter, B.J., Burckart, G.J., Venkataramanan, R. and Rosenthal, J.T. "Cyclosporine Erythromycin interaction". NEJM 313:1416 1417 (1986).
33. Ptachcinski, R.J., Walker, S., Burckart, G.J. and Venkataramanan, R. "Stability and Availability of Cyclosporine Stored in Plastic Syringes". Am J Hosp Pharm 43:692 694 (1986).
34. D'Souza, M., Venkataramanan, R., D'Mello, A. and Niphadkar, R. "An Alternative Pro-drug Approach for Reducing Pre-systemic Metabolism of Drugs". Inter J. Pharmaceutics 31: 165 167 (1986).
35. Ptachcinski, R.J., Burckart, G.J. and Venkataramanan, R. "Cyclosporine Concentration Determinations for Monitoring and Pharmacokinetic Studies" Commentary. J Clin Pharmacol 26:358 366 (1986).
36. Venkataramanan, R., Perez, H.D., Schwinghammer, T., Burckart, G.J., Ptachcinski, R.J., Van Thiel, D.H. and Starzl, T.E. "Effect of Bile on Cyclosporine Absorption in Dogs". Res Comm Chem Pathol. Pharmacol. 53: 137 140 (1986).
37. Venkataramanan, R., Burckart, G.J., Ptachcinski, R.J., Blaha, R., Logue, L.W., Bahnson, A., Giam, C.S. and Brady, J. "Leaching of Diethylhexyl Phthalate from Polyvinyl Chloride Bags into Intravenous Cyclosporine Solution". Am J Hosp Pharm 43: 2800 2802 (1986).
38. Burckart, G.J., Ptachcinski, R.J., Venkataramanan, R., Iwatsuki, S., Esquivel, C., Van Thiel, D.H. and Starzl, T.E. "Cyclosporine Trough Concentration Monitoring in Liver Transplant Patients". Transplant Proc 18:188 193 (1986).
39. Burckart, G.J., Venkataramanan, R., Ptachcinski, R.J., Starzl, T.E., Griffith, B.P., Hakala, T.R., Rosenthal, J.T., Hardesty, R.L., Iwatsuki, S., Brady, J., and Van Thiel, D.H. "Cyclosporine Pharmacokinetic Profiles in Liver, Heart, and Kidney Transplant Patients as Determined by HPLC". Transplant Proc 18:129 136 (1986).
40. Burckart, G.J., Starzl, T.E., Venkataramanan, R., Hashim, H., Wong, L., Wang, P., Makowka, L., Zeevi, A., Ptachcinski, R.J., Knapp, J.E., Iwatsuki, S., Esquivel, C., Sanghvi, A. and Van Thiel, D.H. "Excretion of Cyclosporine and Its Metabolites in Human Bile". Transplant Proc 18:46 49 (1986).
41. Makowka, L., Svanas, G., Esquivel, C., Venkataramanan, R., Todo, S., Iwatsuki, I., Van Thiel, D. and Starzl, T.E. "Effect of Cyclosporine on Hepatic Regeneration". Surgical Forum 37:352 354 (1986).
42. Ptachcinski, R.J., Venkataramanan, R., Burckart, G.J., Gray, J.A., Van Thiel, D.H., Sanghvi, A., Rosenthal, J.T. "Cyclosporine Kinetics in Healthy Volunteers". J Clin Pharmacol 27:243 248 (1987).
43. Venkataramanan, R., Todo, S., Zaghloul, I., Lynch, S., Kam, I., Ptachcinski, R.J., Burckart, G.J. and Starzl, T.E. "Comparative Pharmacokinetics of Cyclosporine and NVa2 Cyclosporine in Dogs". Transplant Proc 19:1265 1266 (1987).
44. Takaya, S., Zaghloul, I., Iwatsuki, S., Starzl, T.E., Noguchi, T., Ohmori, Y., Burckart, G.J., Ptachcinski, R.J. and Venkataramanan, R. "Effect of Liver Dysfunction on Cyclosporine Pharmacokinetics". Transplant Proc 19:1246 1247 (1987).
45. Ericzon, B.G., Todo, S., Lynch, S., Kam, I., Ptachcinski, R.J., Burckart, G.J., Van Thiel, D.H., Starzl, T.E. and Venkataramanan, R. "Role of Bile and Bile Salts on Cyclosporine Absorption in Dogs". Transplant Proc 19:1248 1249 (1987).
46. Ptachcinski, R.J., Hakala, T.R., Rosenthal, J.T., Venkataramanan, R., Burckart, G.J., Taylor, R.J., and Carpenter, B.J. "Cyclosporine High Dose Steroid Interaction in Renal Transplant Recipients: Assessment by HPLC". Transplant Proc 19:1728 1729 (1987).
47. Burckart, G.J., Fricker, F.J., Venkataramanan, R., Ptachcinski, R.J., Hardesty, R.A., Trento, A., Howrie, D. and Griffith, B.P. "Cyclosporine Kinetics in Pediatric Patients with Congestive Heart Failure". Transplant Proc 19:1528 1529 (1987).
48. Zaghloul, I., Ptachcinski, R.J., Burckart, G.J., Van Thiel, D.H., Starzl, T.E. and Venkataramanan, R. "Blood Protein Binding of Cyclo¬sporine in Transplant Patients". J Clin Pharmacol 27:240 242 (1987).
49. Burckart, G.J., Ptachcinski, R.J., Jones, D.H., Howrie, D.L., Venkataramanan, R. and Starzl, T.E. "Impaired Clearance of Ceftizoxime and Cefotaxime after Orthotopic Liver Transplantation". Antimicro Agents and Chemother 31:323 324 (1987).
50. Burckart, G.J., Wang, C.P., Venkataramanan, R. and Ptachcinski, R.J. "Cyclosporine Metabolites". Transplantation 43:932 (1987).
51. Venkataramanan, R.V., Warty, V.S., Zemaitis, M.A., Sanghvi, A.J., Burckart, G.J., Todo, S., Makowka, L. and Starzl, T.E. "Biopharmaceutical Aspects of FR 900506". Transplant Proc 19:30 35 (1987).
52. Bowers, L., Demers, L., Freeman D., Moyer T., Sanghvi, A., Seltman, H., Shaw, L.M., Venkataramanan, R. "Critical Issues in Cyclosporine Monitoring: Report of the Task Force on Cyclosporine Monitoring". Clin Chem 33/7:1269 1288 (1987).
53. D'Souza, M.J., Zemaitis, M.A., Burckart, G.J. and Venkataramanan, R. "Simple High Performance Liquid Chromatographic Method for Simultaneous Determination of Aminopyrine and Its Metabolites". J Chrom 421: 198 205 (1987).
54. Burckart, G.J., Wang, C.P., Zeevi, A., Venkataramanan, R., Ptachcinski, R.J., Hashem, H., Wong, L., Makowka, L. and Starzl, T.E. "Cyclosporine Metabolites in Human Bile: Recovery and Immunologic Activity". Transplant Proc 20:190 192 (1988).
55. Hashem, H., Venkataramanan, R., Burckart, G., Starzl, T. and Wong, L. "Identification of Aldehydic Metabolites of Cyclosporine in Human Bile". Transplant Proc 20:176 178 (1988).
56. Habucky, K., Venkataramanan, R., Ptachcinski, R.J. and Burckart, G.J. "Effect of Chronic Therapy on Absorption and Disposition of Cyclosporine". Transplant Proc 20:162 163 (1988).
57. Wang, C.P., Burckart, G.J., Venkataramanan, R., Ptachcinski, R.J., Cuellar, R.E., Makowka, L. and Starzl, T.E. "Cyclosporine Metabolite Profiles in the Blood of Liver Transplant Patients". Transplant Proc 20:173 175 (1988).
58. Venkataramanan, R., Wang, C.P., Burckart, G., Ptachcinski, R., Todo, S., Koneru, B. and Starzl, T. "Species specific Cyclosporine Metabolism". Transplant Proc 20:680 683 (1988).
59. Wang, C.P., Burckart, G., Ptachcinski, R., Venkataramanan, R., Schwinghammer, T., Hakala, T., Griffith, B., Hardesty, R., Shadduck, R. and Starzl, T. "Cyclosporine Metabolite Concentrations in Blood in Renal, Liver, Heart, and Bone Marrow Transplant Patients". Transplant Proc 20:591 596 (1988).
60. Zeevi, A., Eiras, G., Burckart, G., Makowka, L., Venkataramanan, R., Wang, C.P., Van Thiel, D.H., Murase, N., Starzl, T.E. and Duquesnoy, R. "Immunosuppressive Effect of Cyclosporine Metabolites from Human Bile on Alloreactive T Cells". Transplant Proc 20:115 121 (1988).
61. Zeevi, A., Venkataramanan, R., Burckart, G., Wang, P., Murase, N., Van Thiel, D.H., Makowka, L., Duquesnoy, R.J. and Starzl, T.E. "Sensitivity of Activated Human Lymphocytes to Cyclosporine and Its Metabolite". Hum Immun 21:143 153 (1988).
62. Takaya, S., Iwatsuki, S., Starzl, T.E., Zaghloul, I., Noguchi, T., Ohmori, Y., Burckart, G.J., Ptachcinski, R.J. and Venkataramanan, R. "Experimental Study About the Influence of Liver Dysfunction upon Cyclosporine Pharmacokinetics". Trans Proc 20:154 156 (1988).
63. Mehta, M.U., Venkataramanan, R., Burckart, G.J., Ptachcinski, R.J., Delamos, B., Stachak, S., Van Thiel, D.H., Iwatsuki, S. and Starzl, T.E. "Effect of Bile on Cyclosporine Absorption in Liver Transplant Patients". Br J Clin Pharmac 25: 579 584 (1988).
64. Huang, M L., Venkataramanan, R., Burckart, G.J., Ptachcinski, R.J., Van Thiel, D.H. and Starzl, T.E. "Drug Binding Proteins in Liver Transplant Patients". J Clin Pharmacol 28:505-506, 1988.
65. Caritis, S.N., Lin, L.S., Venkataramanan, R. and Wong, L.K. "Effect of Pregnancy on Ritodrine Pharmacokinetics". Am J Obstet Gynecol 159:328-332, 1988.
66. Wang, C.P., Burckart, G.J. and Venkataramanan, R. "Separation of Cyclosporine Metabolites: Evaluation of High-Pressure Liquid Chromatographic Column Performance". Ther Drug Monit 1988; (10) (3):306-309.
67. Todo, S., Ueda, Y., Demetris, J.A., Imventarza, O., Nalesnik, M., Venkataramanan, R., Makowka, L. and Starzl, T.E. "Immunosuppression of Canine, Monkey, and Baboon Allografts by FK 506: With Special Reference to Synergism with Other Drugs, and to Tolerance Induction." Surgery 104:239-249 (1988).
68. Venkataramanan, R., Koneru, B., Wang, C C.P., Burckart, G.J., Caritis, S.N. and Starzl, T.E. "Cyclosporine and Its Metabolites in Mother and Baby". Transplantation.46:468-469, 1988.
69. Todo, S., Podesta, L., Ueda, Y., Imventarza, O., Casavilla, A., Oks, A., Okuda, K., Nalesnik, M., Venkataramanan, R., and Starzl, T.E. "A Comparison of UW with Other Solutions for Liver Preservation in Dogs". Clin Transplant 3:253-259, 1989.
70. Venkataramanan, R., Huang, M.L., Delamos, B., Burckart, G.J., Ptachcinski, R.J., Van Thiel, D.H. and Starzl, T.E. "Steroid Metabolism in Liver Transplant Patients". Transplant Proc 21:2452, 1989.
71. Venkataramanan, R., Kalp, K., Rabinovitch, M., Cuellar, R., Ptachcinski, R.J., Teperman, L., Makowka, L., Burckart, G.J., Van Thiel, D.H. and Starzl, T.E. "Conjugative Drug Metabolism in Liver Transplant Patients". Transplant Proc 21:2454, 1989.
72. Todo, S., Tzakis, A., Nery, J., Yanaga, K., Venkataramanan, R., Podesta, L., Mieles, L., Scantlebury, V., Gordon, R., Makowka, L., Stieber, A., Koneru, B., Marsh, W., Iwatsuki, S. and Starzl, T.E. "Extended Preservation of Human Liver Grafts with U.W. Solution". JAMA 261:711-714, 1989.
73. Starzl, T.E., Rowe, M., Todo, S., Jaffe, R., Tzakis, A., Hoffman, A.L., Esquivel, C., Porter, K.A., Venkataramanan, R., Makowka, L., and Duquesnoy, R. "Transplantation of Multiple Abdominal Viscera". JAMA 261:1449-1457, 1989.
74. Venkataramanan, R., Habucky, K., Burckart, G.J. and Ptachcinski, R.J. "Clinical Pharmacokinetics of Organ Transplant Patients". Clin Pharmacokin 16:134-161, 1989.
75. Caritis, S.N., Venkataramanan, R., Cotroneo, M. and Chiao, J. P. "Pharmacokinetics of Orally Administered Ritodrine". Am J Obstet Gynecol 161:32-35, 1989.
76. Wang, C.P., Hartman, N.R., Venkataramanan, R., Jardine, I., Lin, F.T., Knapp, J.E., Starzl, T.E. and Burckart, G.J. "Isolation of Ten Cyclosporine Metabolites from Human Bile". Drug Metab Disp 17:292-296, 1989.
77. Kahn, D., Cervio, G., Mazzaferro, V., Venkataramanan, R., Makowka, L., Van Thiel, D.H., and Starzl, T.E. "Correlation Between Dose and Level of Cyclosporine After Orthotopic Liver Transplantation". Transplant Proc 21:2240-2241, 1989.
78. D'mello, A., Satake, M., Todo, S., Takaya, S., Ptachcinski, R.J., Burckart, G.J., Starzl, T.E. and Venkataramanan, R. "Pharmacokinetics of the Cyclosporine Ketoconazole Interaction in Dogs". Res Comm Chem Pathol Pharmacol 64:441-454, 1989.
79. Starzl TE, Todo S, Fung J, Venkataramanan, R, Jain A. FK506 for liver, kidney, and pancreas transplantation. Lancet 2: 1000-1004, 1989.
80. Venkataramanan, R., Jain, A., Cadoff, E., Fung, J., Warty, V., Todo, S., Starzl, T.E. "FK506 Pharmacokinetics and Metabolism-Preclinical and Clinical Studies". Transplant Proc 22:52-56, 1990.
81. Jain, A., Venkataramanan, R., Cadoff, E., Fung, J., Warty, V., Todo, S., and Starzl, T.E. "Effect of Hepatic Dysfunction and T-tube Clamping on FK506 Pharmacokinetics and Through Concentrations". Transplant Proc 22:57-59, 1990.
82. Kang, Y., Mazer, M.A., DeWolf, A.M., Fung, J.J., Gasior, T., Venkataramanan, R., and Starzl, T.E. "Acute Hemodynamic Effects of FK506 During and After Orthotopic Liver Transplantation". Transplant Proc 22:21-22, 1990.
83. Jain, A.B., Fung, J.J., Venkataramanan, R., Todo, S., Alessiani, M., Starzl, T.E. "FK506 Dosage in Human Organ Transplantation". Transplant Proc 22:23-24, 1990.
84. Zeevi. A., Eiras, G., Burckart, G., Jain, A., Krajack, A., Venkataramanan, R., Todo, S., Starzl, T.E., and Duquesnoy, R.J. "Bioassay of Plasma Specimens from Liver Transplant Patients on FK506 Immunosuppression". Transplant Proc 22:60-63, 1990.
85. Todo, S., Fung, J.J., Demetris, A.J., Jain, A., Venkataramanan, R., and Starzl, T.E. "Early Trials with FK506 as Primary Treatment in Liver Transplantation". Transplant Proc 22:13-16, 1990.
86. Caritis, S.N., Venkataramanan, R., Cotroneo, M., Smith, M., Chiao, P.J., and Habucky, K. "Pharmacokinetics and Pharmacodynamics of Ritodrine Following Intramuscular Administration to Pregnant Women". Am J Obstet Gynecol 162:1215-1219, 1990.
87. Mazzaferro, V., Porter K.A., Scott-Foglieni. C.L., Venkataramanan, R., Makowka, L., Rossaro, L., Francavilla, A., Todo, S., Van Thiel, D.H., and Starzl, T.E. The "Hepatotropic Influence of Cyclosporine". Surgery 107:533-539, 1990.
88. Stokar, L.M., Burckart, G.J., D'Souza, M., Cohen, B., and Venkataramanan, R. "Topical Cyclosporine Administration in Rabbits". Res Comm Chem Pathol Pharmacol 68:117-120, 1990.
89. Burckart, G.J., Jain, A., Diven, W., Venkataramanan, R. and Starzl, T.E. "Cyclosporine Measurement by FPIA, PC-RIA, and HPLC Following Liver Transplantation". Transplant Proc 22(3):1319-1322, 1990.
90. Cadoff, E., Venkataramanan, R., Krajack, A., Jain, A.S., Fung, J.J., Todo, S., and Starzl, T.E. "Assay of FK 506 in Plasma". Transplant Proc 22:50-51, 1990.
91. Langrehr, J.M., Lee, K.K.W., Wachs, M.E., Lee, T.K., Stangl, M.J., Venkataramanan, R., Kuntz, H.W. and Schraut, W.H. "Comparison of the Effectiveness of Cyclosporine A in Small-Bowel Transplantation Using Different Rat Strain Combinations". Transplant Proc 22:(6):2533-2535, 1990.
92. Caritis, S., Venkataramanan, R., Darby, M.J., Chiao, J.P., and Krew, M. "Pharmacokinetics of Intravenously Administered Ritodrine Recommendation for Changing the Current Regimen". Am J Obstet Gynecol 162(2):429-437, 1990.
93. Venkataramanan, R., Jain, A., Warty, W.M., A-Elmagd, K., Furakawa, H., Imventarza, O., Fung, J., Todo, S. and Starzl, T.E. "Pharmacokinetics of FK 506 Following Oral Administration. A Comparison of FK 506 and Cyclosporine". Transplant Proc 23:931-933, 1991.
94. Warty, V., Venkataramanan, R., Zendehrouh, P., McKaveney, T., Chao, J., Todo, S. and Starzl, T. "Distribution of FK 506 in Plasma Lipoproteins in Transplant Patients". Transplant Proc 23:954-955, 1991.
95. Zeevi, A., Eiras, G., Kauffman, C., Alessiani, M., Demetris, A.J., Abu-Elmagd, K., Jain, A., Warty, V., Venkataramanan, R., Burckart, G., Starzl, T., Todo, S., Fung, J., and Duquesnoy, R. "Correlation Between Bioassayed Plasma Levels of FK 506 and Lymphocyte Growth from Liver Transplant Biopsies with Histological Evidence of rejection". Transplant Proc 23:1406-1408, 1991.
96. Miles, L., Venkataramanan, R., Yokoyama, I., Warty, V. J. and Starzl, T.E. "Interaction Between FK 506 and Clotrimazole in a Liver Transplant Recipient". Transplantation Vol. 52, 1086-1087, 1991.
97. Schwinghammer, T.L., Przepiorka, D., Venkataramanan, R., Wang, C.P., Burckart, G.J., Rosenfeld, C.S. and Shadduck, R.K. "The Kinetics of Cyclosporine and Its Metabolites in Bone Marrow Transplant Patients". Br Jr Clin Pharmacol 32:323-328, 1991.
98. Steeves, M., Abdallah, H.Y., Venkataramanan, R., Burckart, G.J., Ptachcinski, R.J., Abu-Elmagd, K., Jain, A.K., Fung, F., Todo, S., and Starzl, T.E. In-vitro Interaction of a Novel Immunosuppressant, FK 506, and Antacids". J Pharm Pharmacol 43:574-577, 1991.
99. Toth, A., Abdullah, H.Y., Venkataramanan, R., Teperman, L., Halsf, G., Rabinovitch M., Burckart, G.J., and Starzl, T.E. "Pharmacokinetics of Ceftriaxone in Liver-Transplant Recipients". J Clin Pharmacol 31:722-728, 1991.
100. Przepiorka, D., Shapiro, S., Schwinghammer, T.L., Bloom, E.J., Rosenfield, C.S., Shadduck, R.K. and Venkataramanan, R. "Cyclosporine and Methylprednisolone After Allogenic Marrow Transplantation; Association Between Low Cyclosporine Concentration and Risk of Acute Graft-Versus- Host Disease". Bone Marrow Transplant 7:461-465, 1991.
101. Abu- Elmagd, K., Fung J.J., Alessiani, M., Jain A., Venkataramanan, R., Warty, V., Takaya, S., Todo, S., Day, R. and Starzl, T.E. "The Effect of Graft Function on FK 506 Plasma Levels, Doses and Renal Function: With Particular Reference to the Liver". Transplant 52:71-77, 1991.
102. Jain AB, Todo S, Fung JJ, Venkataramanan, R, Day R, Bryant J, Abu-Elmagd KM, Alessiani, Takaya S, Tzakis A et al. "Correlation of rejection episodes with FK506 dosage, FK506 levels and steroids following primary orthotopic liver transplant. Transplant. proc. 23: 3023-3025, 1991.
103. Wu, Y., Zeng, Y., Suzuki, M., Todo, S., Fung, J., Warty, V.S, Starzl, T.E., Venkataramanan, R. "Interaction Between FK 506 and Cyclosporine in Dogs". Transplant Proc 23:2797-2799, 1991.
104. Habucky, K., Venkataramanan, R., Xiaoshan, R., Fung, J.J., Todo, S., Starzl, T.E. "The Pharmacodynamics of Pentobarbital Following FK 506 Therapy". Transplant Proc 23:2800-2801, 1991.
105. Zeevi, A., Woan, M., Yao, G.Z., Venkataramanan, R., Todo, S., Starzl, T.E., Duquesnoy, RJ. "Comparative in Vitro Studies of the Immunosuppressive Activities of Mycophenolic Acid (MPA) Bredenin (BR), FK 506, CSA and Rapamycin". Transplant Proc 23:2928-2930, 1991.
106. Jain, A.B., Venkataramanan, R., Fung, J., Diven, W., Warty, V., Abu-Elmagd K., Todo, S., Alessiani, M., Starzl, T. "Pharmacokinetics of Cyclosporine and Nephrotoxicity in Orthotopic Liver transplant Patients Rescued With FK506". Transplant Proc 23:2928-2930, 1991.
107. Jain, A.B., Todo, S., Fung, J.J., Day, R., Bryant, J., Abu-Elmagd K., Todo, S., Alessiani, M., Takaya, S., Tzakis, A.G., Warty, V., Venkataramanan, R., Starzl, T. "Correlation of Episodes of Rejections With FK Dosage and FK Level Following Primary Orthotopic Liver Transplantation". Transplant Proc 23:3023-3025, 1991.
108. Jain, A.B., Fung, J.J., Tzakis, A.G., Venkataramanan, R., Abu-Elmagd, K., Alessiani, M., Todo, S., Reyes, J., Warty, V., Starzl, T. "Comparative Study of Cyclosporine and FK 506 Dosage Requirement in Adult and Pediatric Orthotopic Liver Transplant Patient". Transplant Proc 23:2763-2766, 1991.
109. Abu-Elmagd, K., Fung, J., Alessiani, M., Jain, A., Takaya, S., Venkataramanan, R., Warty, V., Shannon, W., Todo, S., Tzakis, A., Starzl, T. "Strategy of FK 506 Therapy in Liver Transplant Patients: The Effect of Graft Function". Transplant Proc 23:2771-2774, 1991.
110. Abu-Elmagd, K., Fung, J., Draviam, R., Jain, A., Alessiani, M., Takaya, S., Venkataramanan, R., Warty, V., Shannon, W., Tzakis, A., Todo, S., Starzl, T. "Four Hour Versus 24 Hour Intravenous Infusion of FK 506 in Primary Liver Recipients". Transplant Proc 23:2767-2770, 1991.
111. Rodriguez-Rilo, H.L., Zeng, Y., Alejandro, R., Carroll, P.B., Bereiter, D., Venkataramanan, R., Tzakis, A.G., Ricordi, C. "In-Vivo Effect of FK 506 on Human Pancreatic Islets". Transplant Proc 23:3164-3165, 1991.
12. Farghali, H., Sakr, M.F., Gasbarrini, A., Venkataramanan, R., Gavaler, J., Starzl, T.E., Van Thiel, D.H. "Effect of FK 506 Chronic Administration on Bromosulphathalein Hepatic Excretion on Rats". Transplant Proc 23:2802-2804, 1991.
113. Venkataramanan, R., Jain, A.K., Warty, V.S., Abu-Elmagd, K., Alessiani, M., Todo, S., Fung, J., Starzl, T.E. "Pharmacokinetics of FK 506 in Transplant Patients". Transplant Proc 23:2736-2740, 1991.
114. Warty, V.S., Venkataramanan, R., Zendehrough, P., Mehta, S., McKaveney, T., Flowers, J., Fung, J., Todo, S., Starzl, T. "Practical Aspects of FK 506 Analysis". Transplant Proc 23:2730-2731, 1991.
115. Zeevi, A., Venkataramanan, R., Warty, V., Eiras, G. Woan, M., Abu-Elmagd, Alessiani, M., Jain, A., Demetris, A.J., Zerbe, T., Fung, J., Todo, S., Starzl, T. and Duquesnoy, R.J. "In Vitro Assessment of FK 506 Immunosuppressive Activity in Transplant Patients". Transplant Proc 23:2897-2899, 1991.
116. Morrisett, J.D., Northrup, S.R., Gotto, A.M., Jr., Starzl, T.E., Venkataramanan, R., Van Thiel, D. and Murase, N. "Effect of FK 506 and Cyclosporine on Plasma Cholesterol Levels in Rabbits". Transplant Proc 23:3185-3187, 1991.
117. Ricordi, C., Zeng, Y., Alejandro, R., Tzakis, A., Venkataramanan, R., Fung, J., Bereiter, D., Mintz, D. H., and Starzl, T. E. "In Vivo Effect of FK 506 on Human Pancreatic Islets". Transplant 52(3):519-522, 1991.
118. Rilo, H.L., Zeng, Y., Alejandro, R., Carroll, P.B., Bereiter, D., Venkataramanan, R., Tzakis, A., Starzl, T. E. and Ricordi, C. "Effect of FK506 on function of human islets of Langerhans. Transplant Proc 23(6):3164-5, 1991.
119. Taromino, D., Abdallah, H., Lough, L., Venkataramanan, R., Burckart, G.J., Ptachcinski, R.J. "Stability and Availability of FK 506 from Intravenous Solutions". Am J Hosp Pharm 49:119-122,1992.
120. Stiff, D.D., Venkataramanan, R., and Prasad, T.N.V. "Metabolism of FK 506 in Differentially Induced Rat Liver". Res Commun Chem Pathol Pharmacol 78:121-124, 1992.
121. Sakr, M., Zetti, G., Farghali, H., Venkataramanan, R., Carrieri, G., Starzl, T., Van Thiel, D. "Effect of Renal Ischemia on Plasma Levels of FK 506 in Rats". Transplant Proc 24(1):425-428, 1992.
122. Jain, A., Venkataramanan, R., Todo, S., Abu-Elmagd, K., Fung, J., Warty, V., Tzakis, A., Reyes, J., Alessiani, M., and Starzl, T.E. "Intravenous, Oral Pharmacokinetics, and Oral Dosing of FK 506 in Small Bowel Transplant Patients". Transplant Proc 24(3) 1181-1182, June 1992.
123. D'Mello, A. P., Venkataramanan, R. V., and Bates, T. R. "Effect of Miconazole on Warfarin Disposition in Rabbits". Drug Metab Dispos 20:572-577, 1992.
124. Murthy, J. N., Chen Y., Warty, V. S., Venkataramanan, R., Donnelly, J. G., Zeevi, A., and Soldin, S. J. "Radio-receptor Assay for Quantifying FK-506 in Whole Blood". Clin Chem 36(7):1307-1310, 1992.
125. Furakawa, H., Imventarza, O., Venkataramanan, R., Cadoff, E., Warty, V., Krazack, A., Todo, S., and Starzl, T.E. "Effect of Bile Duct Ligation of FK Kinetics in Dogs". Transplantation 53:722-725, 1992.
126. Kahn, D., Cervio, G., Mazzaferro, V., Venkataramanan, R., Makowka, L., Van Thiel, D.H. and Starzl, T.E. "Relationship between the dose and whole blood level of cyclosporine after liver and kidney transplantation". Jrnl Clin & Lab Immun 37(4):163-71, 1992.
127. Cai, X., Harnaha, J., Rao, P. N., Flowers, J., Venkataramanan, R., Warty, V., Fung, J., and Starzl, T. E. "Low Doses of FK 506 and its Associated Blood Levels in Allotransplantation of Rat Liver, Heart and Skin". Transplant Proc 24(4):1403-1405, 1992.
128. Ricordi C, Zeng Y, Alejandro R, Tzakis A, Carroll P, Rilo HL, Venkataramanan, R, Fung JJ, Bereiter D, Starzl TE "Effect of FK506 on human pancreatic islets following renal subcapsular transplantation in diabetic nude mice. Transplant. Proc. 24: 1042, 1992
129. Appasamy, R., Tanabe, M., Murase, N., Zarnegar, R., Venkataramanan, R., Van Thiel, D. H., and Michelopoulos, G. K. "Hepatocyte Growth Factor, Blood Clearance, Organ Uptake, and Biliary Excretion in Normal and Partially Hepatectomized Rats". Lab Invest 68:(3):270-276, 1993.
130. Zeevi, A., Yao, G-Z., Venkataramanan, R., Duquesnoy, R.J., Todo, S., Fung J. J., Starzl, T. E. "Comparative in Vitro Studies on the Immunosuppressive Effects of Purine and Pyrimidine Synthesis Inhibitors". Transplant Proc 25:781-783, 1993.
131. Shapiro, R., Venkataramanan, R. and Warty, V. S. "Re: FK 506 and Danazol, Letters to the Editors". Lancet 341, 1344-5, 1993.
132. Jain, A.; Abu-Elmagd, K.; Abdullah, H.; Venkataramanan, R.; Warty V. S.; Fung, J.; Todo, S. and Starzl T.E. "Pharmacokinetics of FK 506 in Liver Transplant Recipients After Continuous Infusion". J Clin Pharmacol 33:606-611, 1993.
133. Zhu, Y., Furukawa, H., Nakamura, K., Hamamoto, I., Wu, Y., Xiaoshan, R., Venkataramanan, R., Todo, S. and Starzl, T.E. "Sodium Lactobionate Sucrose Solution for Canine Liver and Kidney Preservation". Transplant Proc 25(1 Pt 2):1618-9, 1993.
134. Jain, A, Venkataramanan, R, Lever J et al. "FK506 and Pregnancy in Liver Transplant Patients". Transplant 56(6): 1588-1589, 1993.
135. Warty, V., Zuckerman, S., Venkataramanan, R., Lever, J., Fung, J., and Starzl, T. "FK506 Measurement: Comparison of Different Analytical Methods". Therap Drug Monit 15:204-208, 1993.
136. McMichael, J., Lieberman, R., Irish, W., Doyle, J., McCauley, J., V-Thiel, R., Venkataramanan, R., Warty, V., Fung, J. and Starzl, T. E. "Three-Dimensional Surface Mapping and Simulation of FK506 Dose-Level Relationships". Proceedings of the 1993 Western Simulation Multi Conference, Simulation in Health Sciences and Services. (Ed.) Anderson and Katzfer pp. 35-41, 1994.
137. Hopp, L., Lombardozzi, S., Gilboa, N., Ellis, D., Shapiro, R., Webb, M., Weichler, N., Warty, V. S. and Venkataramanan, R. "Removal of FK506 by Continuous Hemofiltration. Report of Two Allograft Recipients With Renal and Liver Failure". Clin Transplant 7:546-551, 1994.
138. Manez, R., Martin, M., Venkataramanan, R., Silverman, D., Jain, A., Warty, V., Gonzalez-P., P., Kusne, S., Starzl, T.E. "Fluconazole Therapy in Transplant Recipients Under FK506 Therapy". Transplant 57:1521-1522, 1994.
139. Tata, P., Stiff, D.D., Subbotina, N., Zemaitis, M.A., Burckart, G.J., Starzl, T.E., Venkataramanan, R. "FK506 (Tacrolimus) Metabolism by Rat Liver Microsomes and Its Inhibition by Other Drugs". Res Comm Chem Pathol Pharmacol 84:35-45, 1994.
140. Kadryl, Z., A-Elmagd, K., Furukawa, H., Todo, S. Venkataramanan, R., Tzakis, A., Manez, R., Reyes, J., Nour, B., Fung, J., Starzl, T. "The Use of the D-Xylose Absorption Test in the Monitoring of Intestinal Allografts". Transplant Proc 26(3): 1645, 1994.
141. Jain, A., Venkataramanan, R., Lever, J., Warty, V., A-Elmagd, K., Furakawa, H., Reyes, J., Nour, B., Arthur, A., Tzakis, A., Todo, S., Fung, J., Starzl, T. "FK 506 in Small Bowel Transplant Recipients: Pharmacokinetics and Dosing Aspects". Transplant Proc 26(3): 1609-1610, 1994.
142. Frezza, E.E., Swaminathan, A., Asrian, A., Doria, C., Bonet, H., Irish, W., Warty, V.S., Todo, S., Starzl, T.E. and Venkataramanan, R. "Water, Sodium, Potassium and D-Xylose Absorption in Canine Small Bowel Allo and Auto Transplantation". Transplant Proc 26(3): 1661, 1994.
143. Muddiman, D., Gusev, A.I., Proctor, A., Hercules, D.M., Venkataramanan, R., Diven, W. "Direct Quantitation of Cyclosporin A in blood by Time-of-FlightMass Spectrometry". Anal Chem 66:2362-2368, 1994.
144. Burckart, G., Venkataramanan, R. "Tacrolimus (FK506): A potent new immunosuppressant, but how should it be used in your transplant center?" Transplant Pharmacy Newsletter Summer 1994.
145. Warty, V.S. and Venkataramanan, R. "New approaches in transplantation therapy". Clin Chem News July 1994 p 34 & 39.
146. Schmitt, M., Nazif, M.M., McKee, K.C., Zullo, T., Venkataramanan, R., Burckart, G., and Habucky, K. "Pharmacokinetics and local responses to submucosal meperidine compared with other routes of administration". Ped Dent 16:3, 1994.
147. Jensen K, Jordan M, Shapiro R, Scantlebury V, Hakala T, Fung J, Starzl T, Venkataramanan, R. "Interaction between tacrolimus and erythromycin Lancet 344: 825, 1994.
148. Warty VS, Zuckerman S, Venkataramanan, R, Lever J, Chao J, McKaveney T, Fung J, Starzl TE. "Tacrolimus Analysis. A comparison of different methods and matrices". Ther. Drug Monit. 17: 159-167, 1995.
149. Kelly PA, Burckart GJ, Venkataramanan, R. "Tacrolimus: A new immunosuppressive agent" Am.J. Health-Syst Pharm. 52: 1521-1535, 1995.
150. Muddiman DC, Gusev AI, Langner KS, Proctor A, Hercules DM, Tata P, Venkataramanan, R, Diven W. Simultaneous quantitation of cyclosporin A and its major metabolites by TOF-SIMS and MALDI/TOF-MS utilizing data analysis techniques. Mass Spectrometry. 30: 1469-1479 (1995)
151. Venkataramanan, R., Swaminathan, A., Prasad T, Jain A, Zuckerman S, Warty, V, McMichael J, Lever J, Burckart, G.J and Starzl TE. "Clinical Pharmacokinetics of Tacrolimus". Clin Pharmacokin. 29(6): 404-430 (1995)
152. Jain AB, Pinna A, Fung J, Warty VS, Singhal AK, Lever J Venkataramanan, R. "Capillary blood versus arterial or venous blood for tacrolimus monitoring in clinical transplantation. Transplantation. 60: 512-514 (1995)
153. Rao PN, Cai X, Venkataramanan, R, Platt JL, Demetris A, Thunberg A, Faltynek C, Starzl T, Kumar P. Reduction of FK506 requirement by combination with polyethylene glycol superoxide dismutase in orthotopic liver transplantation. J. Allergy & Clinical Immunology. 95: 1276-1281, 1995
154. Gusev AI, Muddiman DC, Proctor A, Sharkey A, Hercules DM, Tata PNV, Venkataramanan, R. A quantitative study of hepatic metabolism of tacrolimus in baboons using SIMS and MALDI mass spectrometry" Rapid Communications in Mass Spectrometry. 10: 1215-1218, 1996.
155. Yland MJ, Todo S, Zhu Y, Suzuki T, Hamada H, Zhang S, Subbotino VM, Takeyoshi I, Doria C, Hikida S, Nemoto A, Venkataramanan, R, Tata P, Bernardo JF. An automated and portable low flow pulsatile perfusion system for organ preservation. Transplant International. 9: 535-540, 1996.
156. Tata PNV, Subbatina, Burckart G, Swaminathan A, Gusev AI, Hercules DM, Venkataramanan, R. "Metabolism of tacrolimus (FK506) in rats-effect of rifampin and dexamethasone. Res Communications in Molecular Pathology and Pharmacology 96: 107-110, 1997.
157. Jain A, Venkataramanan, R, Fung JJ, Gartner JC, Lever J, Balan V, Warty V, Starzl TE. Pregnancy following liver transplantation under tacrolimus. Transplantation. 64: 559-565, 1997.
158. Bergman I, Burckart G, Pohl CR, Venkataramanan, R, Barmada MB, Griffin JA. Pharmacokinetics of intrathecal administration of IgG and IgM antiganglioside antibodies in rats and monkey. J. Pharmacol. Expt. Therap.284: 111-115, 1998.
159. Burckart G, Frye RF, Kelly P, Branch R, Jain A, Fung JJ, Starzl TE, Venkataramanan, R. Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6 hydroxylation. Clinical Pharmacol.Therap. 63: 296-302, 1998.
160. Murray M, Grogan T, Lever J, Warty V, Fung J, Venkataramanan, R. Comparison of tacrolimus absorption in transplant patients receiving continuous versus interrupted enteral nutritional feedings. Annals of Pharmacotherapy 32: 633-636, 1998.
161. Venkataramanan, R, McCombs JR, Zuckerman S, McGhee B, Pisupati J, Dice J. Stability of Mycophenolate Mofetil as an extemporaneous suspension. Annals of Pharmacotherapy. 32: 755-757, 1998.
162. Pham SM, Shears LL, Kawaharada N, Venkataramanan, R, Seghal S. High local production of nitric oxide as a possible mechanism by which rapamycin prevents transplant arteriosclerosis. Transplant.Proc.30: 953-954,1998.
163. Shaw L, Nicholls A, Hale M, Venkataramanan, R, Armstrong V, Ollerich M, et al. Therapeutic monitoring of Mycophenolic acid A consensus panel report. Clinical Biochemistry. 31: 317-322, 1998.
164. Whalen, B., Tata P.N.V., Burckart GJ, Venkataramanan, R. "Species differences in the hepatic and gut metabolism of immunosuppressive drug cyclosporine. Xenobiotica. 29: 3-9, 1999.
165. Bergman I, Pohl CR, Venkataramanan, R, Stabin M, Barmada MA, Griffin JA, Cheung NV. Intrathecal administration of an antiganglioside antibody results in specific accumulation within meningeal neoplastic xenografts in nude rats. J. Immunotherapy.22: 114-123, 1999.
166. Jain AB, Hamad I, Zuckerman S, Zhang S, Warty V, Fung JJ, Venkataramanan, R. Effect of T tube clamping on the pharmacokinetics of Mycophenolic acid in liver transplant patients on oral therapy of mycophenolate mofetil. Liver Transplantation and Surgery 5:101-106, 1999.
167. Shaw L, Holt D, Keown P, Venkataramanan, R, Yatscoff R. Current opinions in therapeutic drug monitoring of immunosuppressive drugs. Clinical Therapeutics. 21: 1632-1652, 1999.
168. Ramachandran V, Kostrubsky VE, Komoroski B, Zhang S, Esplen JE, Strom SC, Venkataramanan, R. Troglitazone increases CYP3A protein and activity in primary cultures of human hepatocytes. Drug Metabolism and Disposition.27: 1194-1199, 1999.
169. Kostrubsky VE, Ramachandran V, Venkataramanan, R, Dorko K, Esplen JE, Zhang S, Sinclair JF, Wrighton SA, Strom SC. Induction of enzymatically active CYP3A by taxol or rifampin in human hepatocyte cultures. Drug Metabolism and Disposition. 27: 887-894, 1999.
170. Casele HL, Laifer SA, Woelkers DA, Venkataramanan, R. Changes in the pharmacokinetics of low molecular weight heparin enoxaparin during pregnancy. Amer. J. Obst. Gynec. 181: 1113-1117, 1999.
171. McFarlane GD, Scheller DG, Ersfeld DL, Shaw LM, Venkataramanan, R, Sarkozi L, Mullins R, Fox BR. Analytical Validation of PRO-Trac II ELISA for the determination of Tacrolimus (FK506) in whole blood. Clin. Chem. 45:1449-1458, 1999
172. McFarlane GD, Shaw LM, Venkataramanan, R, Mullins R, Scheller D, Ersfeld D. Analysis of whole blood tacrolimus concentrations in Liver Transplant patients exhibiting impaired liver function. Ther.Drug. Monit.21: 585-592, 1999.
173. Agarwala S, Ou J, Zuckerman S, Burckart G, Venkataramanan, R. Effect of co-administration of cotrimaxazole on tacrolimus induced nephrotoxicity. Renal failure. 21: 635-645, 1999.
174. Kostrubsky VE, Sinclair, JF, Ramachandran V, Venkataramanan, R, Wen YH, Kindt E, Galchev V, Rose K, Sinz M, Strom SC. The role of conjugation in hepatotoxicity of Troglitazone in human and porcine hepatocyte cultures. Drug Metabolism and Disposition. 28: 1198-1201, 2000.
175. Agarwala S, Khanna A, Ou J, Rui S, Zuckerman S, Venkataramanan, R. Amphoterecin B does not potentiate tacrolimus induced nephrotoxicity in rats. Research Communications in Pharmacology and Toxicology 5: 57-73, 2000.
176. Mitruka SN, Won A, McCurry KR, Zeevi A, McKaveney T, Venkataramanan, R, Iacono A, Griffith BP, Burckart GJ. In the lung aerosol cyclosporine provides a regional advantage over intramuscular cyclosporine. J Heart Lung Transplant 19:969-975; 2000.
177. Venkataramanan, R, Ramachandran V, Komoroski B, Zhang S, Strom S. Milk Thistle, an herbal product decreases the activity of drug metabolizing enzymes in primary cultures of human hepatocytes. Drug Metabolism and Disposition. 28: 1270-1273, 2000.
178. John L, Matzke G, Burckart GJ, Venkataramanan, R. Generic substitution of immunosuppressant medications in organ transplantation. Nephrol News Issues. 14: S5-8. 2000.
179. Jain A, Venkataramanan, R, Hamad I, Zuckerman S, Lever J, Warty VS, and Fung JJ. Pharmacokinetics of Mycophenolic acid after Mycophenolate Mofetil administration in liver transplant patients treated with tacrolimus. J. Clin. Pharmacol. 41 : 268-276, 2001.
180. Venkataramanan R, Fitzsimmons WF, McFarlane GD, Scheller D, Ersfeld D, Frick M, Virji M, Jain A, Brayman K, Shaked A. Clinical Utility of monitoring Tacrolimus blood concentrations in Liver Transplant Patients. J. Clin. Pharmacol. 41: 1-10, 2001.
181. Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, Murel P, Relling M, Brimer C, Yasuda K, Venkataramanan, R, Strom S, Thummel K, Boguski MS, Scheutz E. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nature Genetics. 27: 383-391, 2001.
182. Sindhi R, Webber S, Venkataramanan, R, McGhee W, Philipps S, Smith A, Baird C, Iurlano K, Mazariegos G, Cooperstone B, Holt DH, Zeevi A, Fung J, Reyes J. Sirolimus for rescue and primary immunosupression in transplanted children receiving tacrolimus. Transplantation. 72: 851-855, 2001.
183. Mamun A, Venkataramanan, R, Logar AJ, Rao AS, Griffith B, Keenan R, Stanton D, Shapiro R, Fung JJ, Zeevi A. Quantitation of immunosuppression by FK506 using flow cytometric analysis of IL-2 and INF-g inhibition in peripheral blood T-cells. Therapeutic Drug Monitoring 23: 354-362, 2001.
184. Shuetz EG, Strom S, Yasuda K, Lecureur V, Assem M, Brimer C, Lamba J, Kim R, Ramachandran V, Komoroski K, Venkataramanan, R, Cai H, Sinal CJ, Gonzalez FJ, Schuetz JD. Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors transporters and cytochrome P450. J. Biological Chemistry. 276: 39411- 39418, 2001
185. MacFarlane G, Venkataramanan, R, McDiarmid SV, Pirsch J, Scheller DG, Ersfeld DL, Fitzsimmons WE. Therapeutic drug monitoring of tacrolimus in pediatric liver transplant patients. Pediatric Transplantation. 5: 119-124, 2001
186. Iwanami K, Ishikawa T, Okuda T, Zhu Y, Tuerler A, Moore BA, Zhang S, Bauer AJ, Venkataramanan, R, Abu-Elmagd K, Starzl TE, Nalesnik MA, Murase N. Long-term function and morphology of intestinal allografts in outbred canine transplantation model. Transplant Proc. 34: 994-5, 2002.
187. Ishihikawa T, Iwanami K, Okuda T, Zhu Y, Fukuda A, Zhang S, Ou J, Nalesnik MA, Venkataramanan, R, Murase N. Intestinal function and morphology after ex vivo irradiated small bowel transplantation. Transplant Proc. 34(3) :988-9, 2002.
188. Muder R, Agarwala S, Mirani A, Gayowski T, Venkataramanan, R. Pharmacokinetics of cefoperazone and sulbactam in liver transplant patients. J. Clin. Pharmacol. 42 :644-650, 2002.
189. Agarwala S, Culligan E, Jain A, McCauley J, Shapiro R, Chakrabarti P, Burckart G. Evaluation of renal function in transplant patients on chronic tacrolimus therapy. J. Clinical Pharmacology 42: 798-805, 2002.
190. Jain AB, Venkataramanan, R, Shapiro R, Scantlebury V, Potdar S, Bonham A, Pokharna R, Rohal S, Ragni M, Fung JJ. The interaction between tacrolimus and anti retroviral agents in HIV positive liver and kidney transplant patients. Transplant. Proceedings 34: 1540-1541, 2002.
191. Jain AB, Kashyap R, Venkataramanan, R, Eghtesad B, Obaid S, Emad A, Fung JJ. Ribavirin Dose modification based on renal function in liver transplant patients with Hepatitis C virus infection. Liver Transplantation 8: 1007-1013, 2002.
192. Jain AB, Venkataramanan, R, Fridell JA, Gadomski M, Shaw L, Ragni M, Fung JJ. Nelfinavir, a protease inhibitor, increases sirolimus levels in a liver transplant patient: A case report. Liver Transplantation 8: 838-840, 2002.
193. Jain AB, Venkataramanan, R, Shapiro R, Scantlebury V, Potdar S, Bonham A, Ragni M, Fung JJ. The interaction anti retroviral agents and tacrolimus liver and kidney transplant patients. Liver Transplantation 8: 841-845, 2002.
194. Venkataramanan, R, Zhang S, Gayowski T, Singh N. Voriconazole Inhibition of the Metabolism of Tacrolimus in a Liver Transplant Recipient and in Human Liver Microsomes. Antimicrobial Agents and Chemotherapy 46: 3091-3093, 2002.
195. Sindhi R, Webber S, Goyal R, Reyes J, Venkataramanan, R, Shaw L. Pharmacodynamics of sirolimus in transplanted children receiving tacrolimus. Transplant Proc. 34: 1960, 2002.
196. Ishikawa T, Iwanami K, Okuda T, Zhu, Y, Fukuda A, Zhang S, Ou J, Nalesnick M, Venkataramanan, R, Murase N. Morphology and function of canine small intestinal autographs: With particular interest in the influence of ex vivo graft irradiation. J Gastrointest Surg. 7:662-671, 2003.
197. Carcillo JA, Adedoyin A, Burckart GJ, Frye RF, Venkataramanan, R, Knoll C, Thummel K, Roskos L, Wilson JW, Sereika S, Romkes M, Branch RA. Coordinated Intrahepatic and Extrahepatic Regulation of CYP2D6 in health and following Liver Transplantation. Clin.Pharmacol. Ther. 73: 456-467, 2003.
198. Burckart, GJ, Iacono, A, Smaldone, V, Eldon, M, Venkataramanan, R, Dauber, J, Zeevi, A, McKaveney, T, Griffith, BP. Cyclosporine pharmacokinetics after aerosolization in lung transplant patients. Pharmaceutical Research 2003; 20: 252-256.
199. Fridell JA, Patel K, Venkataramanan, R, Virji M, Jain AB. Phenytoin decreases the blood concentrations of sirolimus in a liver transplant recipient: a case report. Therapeutic Drug Monitoring. 25: 117-119, 2003.
200. Shaw LM, Koreka M, Venkataramanan, R, Goldberg L, Bloom R, Brayman KL, Mycophenolic acid pharmacodynamics and pharmacokinetics provide a basis for rationale monitoring strategies. Am. J. Transplant. 2003: 3: 534-542.
201. Jain A, Venkataramanan, R, Eghtesad B, Marcos A, Ragni M, Shapiro R, Rafail AB, Fung, J. Effect of co administered lopinavir and ritonavir (Kaletra) on tacrolimus blood concentration in liver transplantation patients. Liver Transplantation 9: 954-960, 2003.
202. Mahnke CB, Sutton RM, Venkataramanan, R, Michaels M, Kurland G, Boyle GJ, Law YM, Miller SA, Pigula FA, Gandhi S, Webber SA. Tacrolimus dose requirements after initiation of azole antifungal therapy in pediatric thoracic organ transplantation. Pediatric Liver Transplantation. 7:474-479, 2003.
203. Iwanami K, Ishikawa T, Nalesnik MA, Okuda T, Neto JS, Zhu Y, Turler A, Moore BA, Bauer AJ, Venkataramanan, R, Murase N.Long-term function and morphology of intestinal autografts and allografts in out bred dogs. Am J Transplant. 2003;3(9):1083-90.
204. Malik SI, Painter MJ, Venkataramanan, R, Alvin JD. Phenytoin and phenobarbital stable isotope studies in neonates. Pediatr Neurol. 2003; 29(5):376-80.
205. Bernard J. Komoroski, Shimin Zhang, Hong Bo Cai, J. Matthew Hutzler, Reginald F. Frye, Timothy S. Tracy, Stephen C. Strom, Thomas Lehmann, Catharina Ang, Yan Yan Cui, and Raman Venkataramanan. Induction and Inhibition of CYP enzymes by the St. John’s Wort Constituent Hyperforin in Human Hepatocyte Cultures. Drug Metabolism and Disposition 32: 512-518, 2004.
206. Marika Schubert, Raman Venkataramanan, David W Holt, Leslie M Shaw, William McGhee, Jorge Reyes, Steve Webber, Rakesh Sindhi. Pharmacokinetics of Sirolimus (SRL) and Tacrolimus in Pediatric Organ Transplant Recipients. American Journal of Transplantation 2004:4: 767-773.
207. Schuetz EG, Relling MV, Kishi S, Yang W, Das S, Chen P, Cook EH, Rosner GL, Pui CH, Blanco JG, Edick MJ, Hancock ML, Winick NJ, Dervieux T, Amylon MD, Bash RO, Behm FG, Camitta BM, Raimondi SC, Goh BC, Lee SC, Wang LZ, Fan L, Guo JY, Lamba J, Lim R, Lim HL, Ong AB, Lee HS, Kuehl P, Zhang J, Lin Y, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, Maurel P, Brimer C, Yasuda K, Venkataramanan, R, Strom S, Thummel K, Boguski MS. PharmGKB Update: II. CYP3A5, Cytochrome P450, Family 3, Subfamily A, Polypeptide 5. Pharmacol Rev. 2004; 56(2):159.
208. Venkataramanan, R and Shaw, LM. Therapeutic Monitoring of Mycophenolic acid in Liver transplant patients. Editorial. Liver Transplantation 2004; 10: 503-505.
209. Capitano B, Nicolau DP, Potoski BA, Byers K, Horowitz M, Venkataramanan, R and Paterson DL. Meropenem administered as a prolonged infusion to treat serious gram-negative nervous system infection. Pharmacotherapy 2004: 24:803-807.
210. Cho EK, Han DJ, Kim SC, Burckart GJ, Venkataramanan, R, Oh JM. Pharmacokinetic study of mycophenolic acid in Korean kidney transplant patients. J. Clin. Pharmacol. 2004: 44: 743-750.
211. Dympna K, Madariaga JR, Yin L, Sudo Y, Subbotin V, Totsuka E, Ishii T, Lee MC, Gutierrez J, Costa, Zhu Y, Zhang S, Wu D, Fan J, Zang Y, Zhou G, Fukuda A, Venkataramanan R, Demetris AJ, Fung JJ. Porcine partial liver transplantation: A novel model for small for size liver graft. Liver Transplantation. 2004; 10: 253-263.
212. Tian H, Ou J, Strom S, Venkataramanan, R. Pharmacokinetics of tacrolimus and mycophenolic acid are altered but recover at different times during hepatic regeneration in rats. Drug Metabolism and Disposition. 33: 329-335 2005.
213. Pisupati J, Jain A, Burckart G, Hamad I, Zuckerman S, Fung JJ, Venkataramanan, R. Intraindividual and interindividual variations in the pharmacokinetics of mycophenolic acid in liver transplant patients. J. Clin.Pharmacol. 2005: 45: 34-41.
214. Liu S, Frye R, Branch RA, Venkataramanan, R, Fung JJ, Burckart GJ. Effect of age and postoperative time on cytochrome P450 enzyme activity following liver transplantation. J. Clin.Pharmacol 2005 Jun;45(6):666-73.
215. Tracy TS, Venkataramanan, R, Glover DD, Caritis SN, Temporal Changes in CYP1A2, CYP2D6 and CYP3A Activity During Pregnancy. American Journal of Obstetrics and Gynecology 2005; 192: 633-639.
216. Sindhi R, Seward J, Mazariegos G, Seward L, Smith A, Kosmach B, Venkataramanan, R. Replacing calcineurin inhibitors with mTOR inhibitors in children.
Pediatr Transplant. 2005 Jun;9(3):391-7.
217. Feng Y, Zhang S, Strom SC, Venkataramanan, R. Determination of 13-O-demethylated tacrolimus in human liver microsomal incubates using liquid chromatography-mass spectrometric assay. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jul 5;821(1):31-7.
218. Tian H, Ou J, Strom S, Venkataramanan, R. Activity and expression of various forms of UGTs are differentially regulated during hepatic regeneration in rats. Pharm.Res 2005: 22: 2007-2015
219. Komoroski BJ, Praise RA, Egorin M, Strom SC, Venkataramanan, R. Effect of St. John’s Wort constituent Hyperforin on docetaxel metabolism by human hepatocyte cultures. Clinical Cancer Research. 2005; 11: 6972-6979.
220. Kelly M, Jain A, Kashyap R, Orloff M, Abt P, Wrobble K, Venkataramanan, R, Bozorgzadeh A. Changes in absorption of tacrolimus in a liver transplant recipient after reversal of jejunoileal by pass:case report. Transplant. Proc. 2005; 37: 3165-7.
221. Gong H, Sinz MW, Feng Y, Chen T, Venkataramanan, R, Xie W. Animal models of xenobiotic receptors in drug metabolism and diseases. Methods Enzymol. 2005; 400: 598-618.
222. Jain A, Venkataramanan, R, Egstead B, Gadomski M, Mahanka R, Marcos A, Fung JJ. Long term outcome of adding mycophenolate mofetil to tacrolimus for nephrotoxicity following liver transplantation. Transplantation. 2005; 80: 859-864.
223. Jain A, Venkataramanan, R, Yelochan B, Kashyap R, Marcos A, Fung J. Ribavirin levels in post liver transplant patients treated for recurrent hepatitis C viral infection.
224. Mu Y, Zhang J, Zhang S, Zhou HH, Toma D, Ren S, Huang L, Yaramus M, Baum A, Venkataramanan, R, Xie W. Traditional Chinese medicines Wu Wei Zi (Schisandra chinesis Basil) and Gan Cao *Glycyrrhiza uralensis Fisch) activate pregane X receptor and increase warfarin clearance. J. Pharmacol. Exp. Ther. 2006; 316: 1369-77.
225. Lamba J, Strom S, Venkataramanan, R, Watkins PB, Schuetz E. Influence of MDR1 genotype on the CYP3A inductive phenotype. Clin Pharmacol. Ther. 2006: 79:325-338.
226. Venkataramanan, R, Komoroski B, Strom S. In Vitro and in vivo assessment of herb drug interactions. Life Sci. 2006; 78: 2105-2115.
227. Capitano B, Potoski BA, Hussain S, Zhang S, Paterson DL, Studer SM, McCurry KR, Venkataramanan, R. Intrapulmonary penetration of voriconazole in patients receiving an oral prophylactic regimen. Antimicrob.Agents Chemother. 2006; 50: 1878-80.
228. Venkataramanan, R, Sindhi R. Sirolimus differences between children and adults. Pediatric Transplantation 2006; 10: 872-874.
229. Corchran TE, Venkataramanan, R, Mihelc KM, Marcinkowski AL, Ou J, McCook BM, Weber L, Carey ME, Paterson DL, Pielewski JM, McCurry KR, Hussain S. Aerosol deposition of lipid complex of amphoterecin (Abelcet) in lung transplant patients. Am. J. Transplant. 2006; 6: 2765-2773.
230. Saukkonen JJ, Cohn DL, Jasmer RM, Schenker S, Jereb JA, Nolan CM, Peloquin CA, Gordin FM, Nunes D, Strader DB, Bernardo J, Venkataramanan, R, Sterling TR; ATS (American Thoracic Society) Hepatotoxicity of antituberculous Therapy subcommittee. An official ATS statement: hepatotoxicity of antituberculosis therapy. Am J Respir Crit Care Med. 2006: 174: 935-952.
231. Bodri MS, Rambo TM, Wagner RA, Venkataramanan, R. Pharmacokinetics of metronidazole as a single oral bolus to red rat snakes. Journal of Herpetological Medicine and Surgery 2006; 16: 15-19
232. Ashok Jain, Raman Venkataramanan, Tai Kwong, Ravi Mohanka Mark Orloff, Peter Abt, Randeep Kashyap, Cindy Mack Pam Batzold Adel Bozorgzadeh “Pharmacokinetics of Mycophenolic Acid in Liver Transplant Patients after Intravenous and Oral administration of Mycophenolate Mofetil (MMF)”. Liver Transplantation Liver Transpl. 2007 Jun;13(6):791-6.
233. Reschly EJ, Bainy AC, Mattos JJ, Hagey LR, Bahary N, Mada SR, Ou J, Venkataramanan, R, Krasowski MD. Functional evolution of the vitamin D and pregnane X receptors. BMC Evol Biol. 2007 Nov 12;7(1):222 [Epub ahead of print].
234. Shimin Zhanga, Sripal Reddy Madaa, Don Mattisond, Steve Caritisc, Raman Venkataramanan. For the OPRU network. Development and validation of a high-performance liquid chromatography-mass spectrometric assay for determination of 17-alpha Hydroxyprogesterone Caproate (17-OHPC) in human plasma. J. Chormatography J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):141-7. Epub 2007 Jun 2.
235. Lamba J, Lamba V, Strom S, Venkataramanan, R, Schuetz E. Novel Single Nucleotide Polymorphisms in the Promoter, and Intron 1 of Human Pregnane X Receptor/NR1I2 and Their Association with CYP3A4 Expression. Drug Metab Dispos. 2008 Jan; 36(1):169-81. Epub 2007 Oct 9.
236. Jain A, Venkataramanan, R, Sharma R, Kwong T, Abt P, Orloff M, Kashyap R, Tsoulfas G, Bozorgzadeh A. Pharmacokinetics of Mycophenolic Acid in Live Donor Liver Transplant Patients vs Deceased Donor Liver Transplant Patients. J Clin Pharmacol. 2008 May; 48(5):547-52.
237. Jain A, Venkataramanan, R, Sharma R, Kwong T, Orloff M, Abt P, Kashyap R, Tsoulfas G, Batzold P, Williamson M, Bozorgzadeh A. Pharmacokinetics of tacrolimus in living donor liver transplant and deceased donor liver transplant recipients. Transplantation. 2008 Feb 27; 85(4):554-60.
238. Zhang S, Mada SR, Torch M, Goyal RK, Venkataramanan, R. Development and Validation of a High-Performance Liquid Chromatographic Assay for the Determination of Fluconazole in Human Whole Blood Using Solid Phase Extraction. Ther Drug Monit. 2008 Jun; 30(3):314-319.
239. Yasuda K, Ranade A, Venkataramanan, R, Strom S, Chupka J, Ekins S, Schuetz E, Bachmann K. A Comprehensive in vitro and in silico Analysis of Antibiotics that Activate PXR and Induce CYP3A4 in Liver and Intestine. Drug Metab Dispos. 2008; 36: 1689-1697.
240. Shringi Sharma, Steve Strom, Steve Caritis, Donald Mattison, Raman Venkataramanan. “Identification of cytochrome P450 enzymes involved in the metabolism of 17α-Hydroxyprogesterone Caproate” Drug Metabolism and Disposition Drug Metabolism and Disposition 2008; 36: 1896-19902.
241. Shimin Zhang, Sripal Reddy Mada, Shringi Sharma, Marilyn Torch, Don Mattison, Steve Caritis, Raman Venkataramanan, For the OPRU Network. Simultaneous quantitation of 17-alpha Hydroxyprogesterone Caproate (17-OHPC), 17-alpha Hydroxyprogesterone (17-OHP) and Progesterone (P) in human plasma using high pressure liquid chromatography with Tandem Mass Spectrometry (LC-MS/MS). J. Pharm. Biomed Anal 2008; 48: 1174-1180.
242. Tetsuro Sakai, Raymond M. Planinsic, Michael A. Mathier, Michael E. DeVera, Raman Venkataramanan, Use of Continuous Intravenous Treprostinil in Patients with End Stage Liver Disease Associated with Pulmonary Hypertension – Initial Experience Transplant Int. 2009; 22: 554-561.
243. Solari MG, Washington KM, Sacks JM, Hautz T, Unadkat JV, Horibe EK, Venkataramanan, R, Larregina AT, Thomson AW, Lee WP. Daily topical tacrolimus therapy prevents skin rejection in a rodent hind limb allograft model. Plast Reconstr Surg. 2009 Feb; 123(2 Suppl):17S-25S.
244. Tata PN, Subbotina N, Burckart GJ, Muddiman DC, Gusev AI, Hercules DM, Starzl TE, Venkataramanan, R. Species-dependent hepatic metabolism of immunosuppressive agent tacrolimus (FK-506). Xenobiotica. 2009; 39: 757-65.
245. Sharma S, Ellis EC, Dorko K, Zhang S, Mattison DR, Caritis SN, Venkataramanan, R, Strom SC. Metabolism of 17alpha-hydroxyprogesterone caproate, an agent for preventing preterm birth, by fetal hepatocytes. Drug Metab Dispos. 2010; 38:723-7.
246. H Johnson, K Han, B Capitano, D Blisard, S Husain, P Linden, A Marcos, E Kwak, B Potoski, D Paterson, M Romkes, R Venkataramanan. Pharmacokinetics of Voriconazole in Liver Transplant Recipients. Antimicrobial Agents and Chemotherapy 2010 Feb; 54(2):852-9.
247. J Momper R Venkataramanan T Nolin Non renal drug clearance in CKD: Searching for the path less travelled. Adv Chronic Kidney Dis. 2010: 17: 384-391.
248. Han K, Capitano B, Bies R, Potoski BA, Husain S, Gilbert S, Paterson DL,
McCurry K, Venkataramanan, R. Bioavailability and population pharmacokinetics of
voriconazole in lung transplant recipients. Antimicrob Agents Chemother. 2010 Oct; 54(10):4424-31. Epub 2010 Aug 2. PubMed PMID: 20679503; PubMed Central PMCID: PMC2944566.
249. Husain S, Capitano B, Corcoran T, Studer SM, Crespo M, Johnson B, Pilewski JM, Shutt K, Pakstis DL, Zhang S, Carey ME, Paterson DL, McCurry KR, Venkataramanan, R. Intrapulmonary disposition of amphotericin B after aerosolized delivery of amphotericin B lipid complex (Abelcet; ABLC) in lung transplant recipients. Transplantation. 2010 Dec 15;90(11):1215-9. PubMed PMID: 20881664.
250. Bodnar LM, Himes KP, Venkataramanan, R, Chen JY, Evans RW, Meyer JL, Simhan HN. Maternal serum folate species in early pregnancy and risk of preterm birth. Am J. Clin Nutr. 2010 Oct; 92(4):864-71. Epub 2010 Aug 25. PubMed PMID: 20739422; PubMed Central PMCID: PMC2937585.
251. Momper JD, Zhang S, Randhawa PS, Shapiro R, Schonder KS, Venkataramanan, R.
Determination of cidofovir in human plasma after low dose drug administration using high-performance liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2010 Dec 1;53(4):1015-21. Epub 2010 Jul 6. PubMed PMID: 20673618.
252. Han K, Bies R, Johnson H, Capitano B, Venkataramanan, R. Population pharmacokinetic evaluation with external validation and Bayesian estimator of voriconazole in liver transplant recipients. Clin Pharmacokinet. 2011 Mar;50(3):201-14.
253. Chaiffetz D, Dimartini AF, Venkataramanan, R. Prolonged excretion half-life of 11-nor-9-carboxy-Δ⁹-THC following cessation in a chronic, heavy marijuana user: implications for liver transplant assessment. Psychosomatics. 2011 Mar-Apr;52(2):190-3.
254. Beigi RH, Han K, Venkataramanan, R, Hankins GD, Clark S, Hebert MF, Easterling T, Zajicek A, Ren Z, Mattison DR, Caritis SN; Obstetric-Fetal Pharmacology Research Units Network. Pharmacokinetics of oseltamivir among pregnant and nonpregnant women. Am J Obstet Gynecol. 2011 Jun;204(6 Suppl 1): S84-8.
255. Simhan HN, Himes KP, Venkataramanan, R, Bodnar LM. Maternal serum folate species in early pregnancy and lower genital tract inflammatory milieu. Am J Obstet Gynecol. 2011 Jul;205(1):61. e1-7.
256. Caritis SN, Sharma S, Venkataramanan, R, Rouse DJ, Peaceman AM, Sciscione A, Spong CY, Varner MW, Malone FD, Iams JD, Mercer BM, Thorp JM Jr, Sorokin Y, Carpenter M, Lo J, Ramin S, Harper M; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Pharmacokinetics of 17-hydroxyprogesterone caproate in multifetal gestation. Am J Obstet Gynecol. 2011 Jul;205(1):40. e1-8.
257. Ghonem N, Yoshida J, Stolz DB, Humar A, Starzl TE, Murase N, Venkataramanan, R. Treprostinil, a prostacyclin analog, ameliorates ischemia-reperfusion injury in rat orthotopic liver transplantation. Am J Transplant. 2011 Nov;11(11):2508-16.
258. Momper JD, Ridenour TA, Schonder KS, Shapiro R, Humar A, Venkataramanan, R. The impact of conversion from prograf to generic tacrolimus in liver and kidney transplant recipients with stable graft function. Am J Transplant. 2011Sep;11(9):1861-7.
259. Saini SP, Zhang B, Niu Y, Jiang M, Gao J, Zhai Y, Hoon Lee J, Uppal H, Tian H, Tortorici MA, Poloyac SM, Qin W, Venkataramanan, R, Xie W. Activation of liver X receptor increases acetaminophen clearance and prevents its toxicity in mice. Hepatology. 2011 Dec;54(6):2208-17.
260. Krown SE, Roy D, Lee JY, Dezube BJ, Reid EG, Venkataramanan, R, Han K, Cesarman E, Dittmer DP. Rapamycin with antiretroviral therapy in AIDS-associated Kaposi sarcoma: an AIDS Malignancy Consortium study. J Acquir Immune Defic Syndr.
2012 Apr 15;59(5):447-54.
261. Gramignoli R, Green ML, Tahan V, Dorko K, Skvorak KJ, Marongiu F, Zao W, Venkataramanan, R, Ellis EC, Geller D, Breite AG, Dwulet FE, McCarthy RC, Strom SC. Development and application of purified tissue dissociation enzyme mixtures
for human hepatocyte isolation. Cell Transplant. 2012; 21(6):1245-60.
262. Zhang S, Pillai VC, Mada SR, Strom S, Venkataramanan, R. Effect of voriconazole and other azole antifungal agents on CYP3A activity and metabolism of tacrolimus in human liver microsomes. Xenobiotica. 2012 May; 42(5):409-16.
263. Morgan JA, Cheepala SB, Wang Y, Neale G, Adachi M, Nachagari D, Leggas M, Zhao W, Boyd K, Venkataramanan, R, Schuetz JD. Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice. J Biol Chem. 2012 Apr 27;287(18):14456-66.
264. Huang Y, Lu J, Gao X, Li J, Zhao W, Sun M, Stolz DB, Venkataramanan, R, Rohan LC, Li S. PEG-derivatized embelin as a dual functional carrier for the delivery of paclitaxel. Bioconjug Chem. 2012 Jul 18;23(7):1443-51.
265. Corcoran TE, Venkataramanan, R, Hoffman RM, George MP, Petrov A, Richards T, Zhang S, Choi J, Gao YY, Oakum CD, Cook RO, Donahoe M. Systemic Delivery of Atropine Sulfate by the MicroDose Dry-Powder Inhaler. J Aerosol Med Pulm Drug Deliv. 2012; 1:26.
266. Caritis SN, Simhan HN, Zhao Y, Rouse DJ, Peaceman AM, Sciscione A, Spong CY, Varner MW, Malone FD, Iams JD, Mercer BM, Thorp JM Jr, Sorokin Y, Carpenter M, Lo J, Ramin SM, Harper M; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Relationship between 17- hydroxyprogesterone caproate concentrations and gestational age at delivery in twin gestation. Am J Obstet Gynecol. 2012 Nov;207(5): 396.e1-8.
267. Caritis SN, Sharma S, Venkataramanan, R, Hankins GD, Miodovnik M, Hebert MF, Umans JG, Benedetti T, Mattison D, Zajicek A, Fischer D, Jackson A; Eunice Kennedy Shriver National Institute of Child Health and Human Development Obstetrical-Fetal Pharmacology Research Units Network. Pharmacology and placental transport of 17-hydroxyprogesterone caproate in singleton gestation. Am J Obstet Gynecol. 2012 Nov;207(5): 398.e1-8.
268. Momper JD, Zhao Y, Shapiro R, Schonder KS, Yao G, Randhawa PS, Venkataramanan, R. Pharmacokinetics of low dose cidofovir in kidney transplant recipients with BK virus infection. Transpl Infect Dis. 2013; 1, 15.
269. Cuppett CD, Zhao Y, Caritis S, Zhang S, Zhao W, Venkataramanan, R. Effect of endogenous steroid hormones on 17-alpha-hydroxyprogesterone caproate metabolism. Am J Obstet Gynecol. 2013 Jan;208(1):86. e1-6.
270. Sharma S, Ellis EC, Gramignoli R, Dorko K, Tahan V, Hansel M, Mattison DR, Caritis SN, Hines RN, Venkataramanan, R, Strom SC. Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes. Drug Metab Dispos. 2013; 2: 41, 296-304.
271. Lu J, Huang Y, Zhao W, Marquez RT, Meng X, Li J, Gao X, Venkataramanan, R, Wang Z, Li S. PEG-derivatized embelin as a nanomicellar carrier for delivery of paclitaxel to breast and prostate cancers. Biomaterials. 2013 Feb;34(5):1591-600.
272. Pillai VC, Strom SC, Caritis SN, Venkataramanan, R. A sensitive and specific CYP cocktail assay for the simultaneous assessment of human cytochrome P450 activities in primary cultures of human hepatocytes using LC-MS/MS. J Pharm Biomed Anal. 2013 Feb 23; 74:126-32.
273. Goyal RK, Han K, Wall DA, Pulsipher MA, Bunin N, Grupp SA, Mada SR, Venkataramanan, R. Sirolimus Pharmacokinetics in Early Post Myeloablative Pediatric Blood and Marrow Transplantation. Biol Blood Marrow Transplant. 2013; 73: 2235-2246.
274. Roy D, Sin S, Lucas A Venkataramanan, R, Wang L, Damania B, Dittmer DP. MTOR inhibitors stall Kaposi sarcoma growth by inhibiting essential autocrine growth factors and tumor angiogenesis. Cancer Research 2013; 7: 73.
275. Zhang X, Lu J, Huang Y, Zhao W, Chen Y, Li J, Gao X, Venkataramanan, R, Sun M, Stolz DB, Zhang L, Li S. PEG-farnesylthiosalicylate conjugate as a nanomicellar carrier for delivery of paclitaxel. Bioconjug Chem, 24: 464-472, 2013.
276. Caritis SN, Zhao Y, Bettinger J, Venkataramanan, R. Qualitative and quantitative measures of various compounded formulations of 17-alpha hydroxyprogesterone caproate. Am J Obstet Gynecol, 208: e1-5, 2013.
277. Schnider JT, Weinstock M, Plock JA, Solari MG, Venkataramanan, R, Zheng XX, Gorantla VS. Site-specific immunosuppression in vascularized composite allotransplantation: prospects and potential. Clin Dev Immunol, 2013; 2013:495212.
278. Caritis SN, Zhao Y, Venkataramanan, R, Bettinger J. Reply Am J Obstet Gynecol., 13, 208, 2013 Letter and Commentary.
279. Gramignoli R, Tahan V, Dorko K, Skvorak KJ, Hansel MC, Zhao W, Venkataramanan R, Ellis EC, Jorns C, Ericzon BG, Rosenborg S, Kuiper R, Soltys KA, Mazariegos GV, Fox IJ, Wilson EM, Grompe M, Strom SC. New potential cell source for_hepatocyte transplantation: Discarded livers from metabolic disease liver transplants. Stem Cell Res, 1, 11, 2013.
280. Corcoran TE, Venkataramanan, R, Hoffman RM, George MP, Petrov A, Richards T, Zhang S, Choi J, Gao YY, Oakum CD, Cook RO, Donahoe M. Systemic delivery of atropine sulfate by the MicroDose Dry-Powder Inhaler. J Aerosol Med Pulm Drug Deliv. 2013 Feb;26(1):46-55.
281. Lu J, Huang Y, Zhao W, Chen Y, Li J, Gao X, Venkataramanan, R, Li S. Design, and characterization of PEG-derivatized vitamin E as a nanomicellar formulation for delivery of paclitaxel. Mol Pharm. 2013 Aug 5;10(8):2880-90.
282. Han K, Pillai VC, Venkataramanan, R. Population pharmacokinetics of cyclosporine in transplant recipients. AAPS J. 2013 Oct;15(4):901-12.
283. Kittayaruksakul S, Zhao W, Xu M, Ren S, Lu J, Wang J, Downes M, Evans RM, Venkataramanan, R, Chatsudthipong V, Xie W. Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation. Pharm Res. 2013 Sep;30(9):2199-208.
284. Pillai VC, Venkataramanan, R, Parise RA, Christner SM, Gramignoli R, Strom SC, Rudek MA, Beumer JH. Ritonavir and efavirenz significantly alter the metabolism of erlotinib—an observation in primary cultures of human hepatocytes that is relevant to HIV patients with cancer. Drug Metab Dispos. 2013 Oct;41(10):1843-51.
285. Barbarino JM, Staatz CE, Venkataramanan, R, Klein TE, Altman RB. PharmGKB summary: cyclosporine and tacrolimus pathways. Pharmacogenet Genomics. 2013 Oct;23(10):563-85.
286. Wheeler SE, Borenstein JT, Clark AM, Ebrahimkhani MR, Fox IJ, Griffith L, nman W, Lauffenburger D, Nguyen T, Pillai VC, Prantil-Baun R, Stolz DB, Taylor D, Ulrich T, Venkataramanan, R, Wells A, Young C. All-human microphysical model of metastasis therapy. Stem Cell Res Ther. 2013;4 Suppl 1: S11.
287. Caritis SN, Venkataramanan, R, Thom E, Harper M, Klebanoff MA, Sorokin Y, Thorp JM Jr, Varner MW, Wapner RJ, Iams JD, Carpenter MW, Grobman WA, Mercer BM, Sciscione A, Rouse DJ, Ramin S; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network and Obstetric-Fetal Pharmacology Research Units Network. Relationship between 17-alpha hydroxyprogesterone caproate concentration and spontaneous preterm birth. Am J Obstet Gynecol. 2014 Feb;210(2): 128.e1-6. doi: 10.1016/j.ajog.2013.10.008. Epub 2013 Oct 7. PubMed PMID: 24113254; PubMed Central PMCID: PMC3926421.
288. Chang J, Zhao Y, Zhao W, Venkataramanan, R, Caritis SN; Obstetrical-Fetal Pharmacology Research Units Network. Quality assessment of compounded 17-hydroxyprogesterone caproate. Am J Obstet Gynecol. 2014 Jan;210(1):47. e1-7. doi: 10.1016/j.ajog.2013.09.039. Epub 2013 Nov 4. PubMed PMID: 24200163; PubMed Central PMCID: PMC3939712.
289. Zhang P, Lu J, Huang Y, Zhao W, Zhang Y, Zhang X, Li J, Venkataramanan, R, Gao X, Li S. Design and evaluation of a PEGylated lipopeptide equipped with drug-interactive motifs as an improved drug carrier. AAPS J. 2014 Jan;16(1):114-24. doi: 10.1208/s12248-013-9536-9. Epub 2013 Nov 27. PubMed PMID: 24281690; PubMed Central PMCID: PMC3889538.
290. Beumer JH, Venkataramanan, R, Rudek MA. Pharmacotherapy in cancer patients with HIV/AIDS. Clin Pharmacol Ther. 2014 Apr;95(4):370-2. Doi: 10.1038/clpt.2014.10. pub 2014 Jan 17. PubMed PMID: 24440966; PubMed Central PMCID: PMC4091903.
291. Rytting E, Nanovskaya TN, Wang X, Vernikovskaya DI, Clark SM, Cochran M, Abdel-Rahman SM, Venkataramanan, R, Caritis SN, Hankins GD, Ahmed MS. Pharmacokinetics of ndomethacin in pregnancy. Clin Pharmacokinet. 2014 Jun;53(6):545-51. Doi: 10.1007/s40262-014-0133-6. PubMed PMID: 24493205; PubMed Central PMCID: PMC4164383.
292. Wheeler SE, Borenstein JT, Clark AM, Ebrahimkhani MR, Fox IJ, Griffith L, Inman W, Lauffenburger D, Nguyen T, Pillai VC, Prantil-Baun R, Stolz DB, Taylor D, Ulrich T, Venkataramanan, R, Wells A, Young C. All-human microphysical model of metastasis therapy. Stem Cell Res Ther. 2013;4 Suppl 1: S11. doi: 10.1186/scrt372. Epub 2013 Dec 20. Review. PubMed PMID: 24565274; PubMed Central PMCID: PMC4028965.
293. Gramignoli R, Tahan V, Dorko K, Venkataramanan, R, Fox IJ, Ellis EC, Vosough M, Strom SC. Rapid and sensitive assessment of human hepatocyte functions. Cell Transplant. 2014;23(12):1545-56. doi: 10.3727/096368914X680064. Epub 2014 Apr 4. PubMed PMID: 24702711.
294. Mantha VR, Nair HK, Venkataramanan, R, Gao YY, Matyjaszewski K, Dong H, Li W, Landsittel D, Cohen E, Lariviere WR. Nanoanesthesia: a novel, intravenous approach to ankle block in the rat by magnet-directed concentration of ropivacaine-associated nanoparticles. Anesth Analg. 2014 Jun;118(6):1355-62. doi: 10.1213/ANE.0000000000000175. PubMed PMID: 24722259.
295. Goyal RK, Gehris RP, Howrie D, Cogley KM, Windreich RM, Venkataramanan, R. Phototoxic dermatoses in pediatric BMT patients receiving voriconazole. Pediatr Blood Cancer. 2014 Jul;61(7):1325-8. doi: 10.1002/pbc.24897. Epub 2014 Mar 11. PubMed PMID: 24619922.
296. Zhao Y, Alshabi AM, Caritis S, Venkataramanan, R. Impact of 17-alpha-hydroxyprogesterone caproate on cytochrome P450s in primary cultures of human hepatocytes. Am J Obstet Gynecol. 2014 Oct;211(4): 412.e1-6. doi: 10.1016/j.ajog.2014.03.048. Epub 2014 Mar 26. PubMed PMID: 24681287.
297. Clark AM, Wheeler SE, Taylor DP, Pillai VC, Young CL, Prantil-Baun R, Nguyen T, Stolz DB, Borenstein JT, Lauffenburger DA, Venkataramanan, R, Griffith LG, Wells A. A microphysiological system model of therapy for liver micrometastases. Exp Biol Med (Maywood). 2014 Sep;239(9):1170-9. doi: 10.1177/1535370214532596. Epub 2014 May 12. Review. PubMed PMID: 24821820.
298. Pillai VC, Parise RA, Christner SM, Rudek MA, Beumer JH, Venkataramanan, R. Potential interactions between HIV drugs, ritonavir and efavirenz and anticancer drug, nilotinib--a study in primary cultures of human hepatocytes that is applicable to HIV patients with cancer. J Clin Pharmacol. 2014 Nov;54(11):1272-9. doi: 10.1002/jcph.333. Epub 2014 May 27. PubMed PMID: 24846165.
299. Zhang P, Huang Y, Liu H, Marquez RT, Lu J, Zhao W, Zhang X, Gao X, Li J, Venkataramanan, R, Xu L, Li S. A PEG-Fmoc conjugate as a nanocarrier for paclitaxel. Biomaterials. 2014 Aug;35(25):7146-56. doi: 10.1016/j.biomaterials.2014.04.108. Epub 2014 May 22. PubMed PMID: 24856103; PubMed Central PMCID: PMC4102141.
300. Zhao Y, Bettinger J, Caritis S, Venkataramanan, R. Stability of hydroxyprogesterone caproate alone and in a compounded pharmaceutical product. Am J Health Syst Pharm. 2014 Jul 1;71(13):1120-7. doi: 10.2146/ajhp130466. PubMed PMID: 24939502.
301. Zhang X, Huang Y, Zhao W, Chen Y, Zhang P, Li J, Venkataramanan, R, Li S. PEG-farnesyl thiosalicylic acid telodendrimer micelles as an improved formulation for targeted delivery of paclitaxel. Mol Pharm. 2014 Aug 4;11(8):2807-14. doi: 10.1021/mp500181x. Epub 2014 Jul 11. PubMed PMID: 24987803; PubMed Central PMCID: PMC4123940.
302. Zhang Y, Huang Y, Zhao W, Lu J, Zhang P, Zhang X, Li J, Gao X, Venkataramanan, R, Li S. Fmoc-conjugated PEG-vitamin E2 micelles for tumor-targeted delivery of paclitaxel: enhanced drug-carrier interaction and loading capacity. AAPS J. 2014 Nov;16(6):1282-91. doi: 10.1208/s12248-014-9651-2. Epub 2014 Sep 6. PubMed PMID: 25193267; PubMed Central PMCID: PMC4389742.
303. Feghali M, Venkataramanan, R, Caritis S. Prevention of preterm delivery with 17-hydroxyprogesterone caproate: pharmacologic considerations. Semin Perinatol. 2014 Dec;38(8):516-22. doi: 10.1053/j.semperi.2014.08.013. Epub 2014 Sep 23. PubMed PMID: 25256193; PubMed Central PMCID: PMC4253874.
304. Lu J, Zhao W, Huang Y, Liu H, Marquez R, Gibbs RB, Li J, Venkataramanan, R, Xu L, Li S, Li S. Targeted delivery of Doxorubicin by folic acid-decorated dual functional nanocarrier. Mol Pharm. 2014 Nov 3;11(11):4164-78. doi: 10.1021/mp500389v. Epub 2014 Sep 29. PubMed PMID: 25265550; PubMed Central PMCID: PMC4224520.
305. Zhao Y, Hebert MF, Venkataramanan, R. Basic obstetric pharmacology. Semin Perinatol. 2014 Dec;38(8):475-86. doi: 10.1053/j.semperi.2014.08.011. Epub 2014 Oct 1. PubMed PMID: 25281357.
306. Beigi RH, Venkataramanan, R, Caritis SN. Oseltamivir for influenza in pregnancy. Semin Perinatol. 2014 Dec;38(8):503-7. doi: 10.1053/j.semperi.2014.08.015. Epub 2014 Oct 1. PubMed PMID: 25281358.
307. Rosborough BR, Raïch-Regué D, Liu Q, Venkataramanan, R, Turnquist HR, Thomson AW. Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection. Am J Transplant. 2014 Sep;14(9):2173-80. doi: 10.1111/ajt.12799. Epub 2014 Aug 4. PubMed PMID: 25307040; PubMed Central PMCID: PMC4196715.
308. Wheeler SE, Clark AM, Taylor DP, Young CL, Pillai VC, Stolz DB, Venkataramanan, R, Lauffenburger D, Griffith L, Wells A. Spontaneous dormancy of metastatic breast cancer cells in an all-human liver microphysiologic system. Br J Cancer. 2014 Dec 9;111(12):2342-50. doi: 10.1038/bjc.2014.533. Epub 2014 Oct 14. PubMed PMID: 25314052; PubMed Central PMCID: PMC4264444.
309. Zhang X, Huang Y, Zhao W, Liu H, Marquez R, Lu J, Zhang P, Zhang Y, Li J, Gao X, Venkataramanan, R, Xu L, Li S. Targeted delivery of anticancer agents via a dual function nanocarrier with an interfacial drug-interactive motif. Biomacromolecules. 2014 Nov 10;15(11):4326-35. doi: 10.1021/bm501339j. Epub 2014 Oct 28. PubMed PMID: 25325795; PubMed Central PMCID: PMC4229023.
310. Lu J, Zhao W, Liu H, Marquez R, Huang Y, Zhang Y, Li J, Xie W, Venkataramanan R, Xu L, Li S. An improved D-α-tocopherol-based nanocarrier for targeted delivery of doxorubicin with reversal of multidrug resistance. J Control Release. 2014 Dec 28; 196:272-86. doi: 10.1016/j.jconrel.2014.10.016. Epub 2014 Oct 24. PubMed PMID: 25456831; PubMed Central PMCID: PMC4267990.
311. Pillai VC, Han K, Beigi RH, Hankins GD, Clark S, Hebert MF, Easterling TR, Zajicek A, Ren Z, Caritis SN, Venkataramanan R. Population pharmacokinetics of oseltamivir in non-pregnant and pregnant women. Br J Clin Pharmacol. 2015
Nov;80(5):1042-50. doi: 10.1111/bcp.12691. Epub 2015 Aug 18. PubMed PMID: 26040405; PubMed Central PMCID: PMC4631177.
312. Entringer S, Epel ES, Lin J, Blackburn EH, Buss C, Shahbaba B, Gillen DL, Venkataramanan R, Simhan HN, Wadhwa PD. Maternal Folate Concentration in Early Pregnancy and Newborn Telomere Length. Ann Nutr Metab. 2015;66(4):202-8. doi:
10.1159/000381925. Epub 2015 Jun 9. PubMed PMID: 26067849.
313. Young OM, Shaik IH, Twedt R, Binstock A, Althouse AD, Venkataramanan R, Simhan HN, Wiesenfeld HC, Caritis SN. Pharmacokinetics of cefazolin prophylaxis in obese gravidae at time of cesarean delivery. Am J Obstet Gynecol. 2015
Oct;213(4): 541.e1-7. doi: 10.1016/j.ajog.2015.06.034. Epub 2015 Jun 20. PubMed PMID: 26103528; PubMed Central PMCID: PMC4586370.
314. Beigi RH, Pillai VC, Venkataramanan R, Caritis SN. Oseltamivir for the treatment of H1N1 influenza during pregnancy. Clin Pharmacol Ther. 2015 Oct;98(4):403-5. doi: 10.1002/cpt.179. Epub 2015 Jul 22. Review. PubMed PMID: 26108913.
315. Beumer JH, Pillai VC, Parise RA, Christner SM, Kiesel BF, Rudek MA, Venkataramanan R. Human hepatocyte assessment of imatinib drug-drug interactions - complexities in clinical translation. Br J Clin Pharmacol. 2015 Nov;80(5):1097-108. doi: 10.1111/bcp.12723. Epub 2015 Sep 19. PubMed PMID: 26178713; PubMed Central PMCID: PMC4631182.
316. Zhang P, Li J, Ghazwani M, Zhao W, Huang Y, Zhang X, Venkataramanan R, Li S. Effective co-delivery of doxorubicin and dasatinib using a PEG-Fmoc nanocarrier for combination cancer chemotherapy. Biomaterials. 2015 Oct; 67:104-14. doi: 10.1016/j.biomaterials.2015.07.027. Epub 2015 Jul 15. PubMed PMID: 26210177; PubMed Central PMCID: PMC4550547.
317. Siminerio L, Venkataramanan R, Caritis S. Selective serotonin reuptake inhibitors and childhood motor skill impairment-what can be concluded? BJOG. 2015 Sep 15. doi: 10.1111/1471-0528.13581. [Epub ahead of print] PubMed PMID: 26374134; PubMed Central PMCID: PMC4811734.
318. Feghali M, Venkataramanan R, Caritis S. Pharmacokinetics of drugs in pregnancy. Semin Perinatol. 2015 Nov;39(7):512-9. doi: 10.1053/j.semperi.2015.08.003. PubMed PMID: 26452316; PubMed Central PMCID: PMC4809631.
319. Duong SQ, Lal AK, Joshi R, Feingold B, Venkataramanan R. Transition from brand to generic tacrolimus is associated with a decrease in trough blood concentration in pediatric heart transplant recipients. Pediatr Transplant. 2015 Dec;19(8):911-7. doi: 10.1111/petr.12608. Epub 2015 Oct 25. PubMed PMID: 26497983.
320. Costantine MM, Cleary K, Hebert MF, Ahmed MS, Brown LM, Ren Z, Easterling TR, Haas DM, Haneline LS, Caritis SN, Venkataramanan R, West H, D'Alton M, Hankins G.
Eunice Kennedy Shriver National Institute of Child Health and Human Development Obstetric-Fetal Pharmacology Research Units Network. Safety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: a pilot randomized controlled trial. Am J Obstet Gynecol. 2016 Jun;214(6): 720.e1-720.e17. doi: 10.1016/j.ajog.2015.12.038. Epub 2015 Dec 23. PubMed PMID: 26723196; PubMed Central PMCID: PMC4884459.
321. Shaik IH, Bastian JR, Zhao Y, Caritis SN, Venkataramanan R. Route of administration and formulation dependent pharmacokinetics of 17-hydroxyprogesterone caproate in rats. Xenobiotica. 2016 Feb;46(2):169-74. doi: 10.3109/00498254.2015.1057547. Epub 2015 Jul 7. PubMed PMID: 26153441; PubMed Central PMCID: PMC4809632.
322. Zhao Y, Chen HJ, Caritis S, Venkataramanan R. Development, and validation of a sensitive liquid chromatographic-tandem mass spectrometric method for the simultaneous analysis of granisetron and 7-hydroxy granisetron in human plasma and urine samples: application in a clinical pharmacokinetic study in pregnant subject. Biomed Chromatogr. 2016 Feb;30(2):149-54. doi: 10.1002/bmc.3530. Epub 2015 Jul 21. PubMed PMID: 26053159.
323. Windreich RM, Goyal RK, Joshi R, Kenkre TS, Howrie D, Venkataramanan R. A Pilot Study of Continuous Infusion of Mycophenolate Mofetil for Prophylaxis of Graft-versus-Host-Disease in Pediatric Patients. Biol Blood Marrow Transplant. 2016 Apr;22(4):682-9. doi: 10.1016/j.bbmt.2015.12.013. Epub 2015 Dec 29. PubMed
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324. Li M, Zhao Y, Humar A, Tevar AD, Hughes C, Venkataramanan R. Pharmacokinetics of drugs in adult living donor liver transplant patients: regulatory factors and observations based on studies in animals and humans. Expert Opin Drug Metab
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325. Caritis S, Zhao Y, Chen HJ, Venkataramanan R. Pharmacodynamics of transdermal granisetron in women with nausea and vomiting of pregnancy. Am J Obstet Gynecol.
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326. Zhang H, Nguyen MH, Clancy CJ, Joshi R, Zhao W, Ensor C, Venkataramanan R, Shields RK. Pharmacokinetics of Posaconazole Suspension in Lung Transplant Recipients With and Without Cystic Fibrosis. Antimicrob Agents Chemother. 2016 Mar 28. pii: AAC.00424-16. [Epub ahead of print] PubMed PMID: 27021324.
327. Siminerio LL, Bodnar LM, Venkataramanan R, Caritis SN. Ondansetron Use in Pregnancy. Obstet Gynecol. 2016 May;127(5):873-7. doi:10.1097/AOG.0000000000001375. PubMed PMID: 27054931.
328. Bustos M, Venkataramanan R, Caritis S. Nausea and vomiting of pregnancy - What's new? Auton Neurosci. 2016 May 13. pii: S1566-0702(16)30048-0. doi: 10.1016/j.autneu.2016.05.002. [Epub ahead of print] Review. PubMed PMID:
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329. Lemon LS, Zhang H, Hebert MF, Hankins GD, Haas DM, Caritis SN, Venkataramanan R. Ondansetron Exposure Changes in a Pregnant Woman. Pharmacotherapy. 2016 Sep;36(9): e139-41. doi: 10.1002/phar.1796. Epub 2016 Jul 25. PubMed PMID: 27374186; PubMed Central PMCID: PMC5738660.
330. Hoberman A, Paradise JL, Rockette HE, Jeong JH, Kearney DH, Bhatnagar S, Shope TR, Muñiz G, Martin JM, Kurs-Lasky M, Haralam M, Pope MA, Nagg JP, Zhao W, Miah, MK, Beumer J, Venkataramanan R, Shaikh N. Reduced-Concentration Clavulanate for Young Children with Acute Otitis Media. Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00238-17. doi: 10.1128/AAC.00238-17. Print 2017 Jul. PubMed PMID: 28438923.
331. Kalluri HV, Sacha LM, Ingemi AI, Shullo MA, Johnson HJ, Sood P, Tevar AD, Humar A, Venkataramanan R. Low vitamin D exposure is associated with higher risk of infection in renal transplant recipients. Clin Transplant. 2017 May;31(5). doi: 10.1111/ctr.12955. Epub 2017 Apr 4. PubMed PMID: 28295622.
332. Chen WLK, Edington C, Suter E, Yu J, Velazquez JJ, Velazquez JG, Shockley M, Large EM, Venkataramanan R, Hughes DJ, Stokes CL, Trumper DL, Carrier RL, Cirit M, Griffith LG, Lauffenburger DA. Integrated gut/liver microphysiological systems elucidates inflammatory inter-tissue crosstalk. Biotechnol Bioeng. 2017 Nov;114(11):2648-2659. doi: 10.1002/bit.26370. Epub 2017 Jul 27. PubMed PMID: 28667746; PubMed Central PMCID: PMC5614865.
333. Bustos ML, Caritis SN, Jablonski KA, Reddy UM, Sorokin Y, Manuck T, Varner MW, Wapner RJ, Iams JD, Carpenter MW, Peaceman AM, Mercer BM, Sciscione A, Rouse DJ, Ramin SM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. The association among cytochrome P450 3A, progesterone receptor polymorphisms, plasma 17-alpha hydroxyprogesterone caproate concentrations, and spontaneous preterm birth. Am J Obstet Gynecol. 2017 Sep;217(3): 369.e1-369.e9. doi: 10.1016/j.ajog.2017.05.019. Epub 2017 May 15. PubMed PMID: 28522317; PubMed Central PMCID: PMC5896763.
334. Sun J, Liu Y, Chen Y, Zhao W, Zhai Q, Rathod S, Huang Y, Tang S, Kwon YT, Fernandez C, Venkataramanan R, Li S. Doxorubicin delivered by a redox-responsive dasatinib-containing polymeric prodrug carrier for combination therapy. J Control Release. 2017 Jul 28; 258:43-55. doi: 10.1016/j.jconrel.2017.05.006. Epub 2017 May 12. PubMed PMID: 28501705; PubMed Central PMCID: PMC5525542.
335. Sun JJ, Chen YC, Huang YX, Zhao WC, Liu YH, Venkataramanan R, Lu BF, Li S. Programmable co-delivery of the immune checkpoint inhibitor NLG919 and chemotherapeutic doxorubicin via a redox-responsive immunostimulatory polymeric prodrug carrier. Acta Pharmacol Sin. 2017 Jun;38(6):823-834. doi: 10.1038/aps.2017.44. Epub 2017 May 8. PubMed PMID: 28504251; PubMed Central PMCID: PMC5520195.
336. Ensor CR, Yousem SA, Marrari M, Morrell MR, Mangiola M, Pilewski JM, D'Cunha J, Wisniewski SR, Venkataramanan R, Zeevi A, McDyer JF. Proteasome Inhibitor Carfilzomib-Based Therapy for Antibody-Mediated Rejection of the Pulmonary Allograft: Use and Short-Term Findings. Am J Transplant. 2017 May;17(5):1380-1388. doi: 10.1111/ajt.14222. Epub 2017 Mar 9. PubMed PMID: 28173620.
337. Unadkat JV, Schnider JT, Feturi FG, Tsuji W, Bliley JM, Venkataramanan R, Solari MG, Marra KG, Gorantla VS, Spiess AM. Single Implantable FK506 Disk Prevents Rejection in Vascularized Composite allotransplantation. Plast Reconstr Surg. 2017 Feb;139(2):403e-414e. doi:10.1097/PRS.0000000000002951. PubMed PMID: 28121868.
338. Serra AE, Lemon LS, Mokhtari NB, Parks WT, Catov JM, Venkataramanan R, Caritis SN. Delayed villous maturation in term placentas exposed to opioid maintenance therapy: a retrospective cohort study. Am J Obstet Gynecol. 2017 Apr;216(4): 418.e1-418.e5. doi: 10.1016/j.ajog.2016.12.016. Epub 2016 Dec 23. PubMed PMID: 28024988.
339. Moore CA, Iasella CJ, Venkataramanan R, Lakkis FG, Smith RB, McDyer JF, Zeevi A, Ensor CR. Janus kinase inhibition for immunosuppression in solid organ transplantation: Is there a role in complex immunologic challenges? Hum Immunol. 2017 Feb;78(2):64-71. doi: 10.1016/j.humimm.2016.12.005. Epub 2016 Dec 18. Review. PubMed PMID: 27998802.
340. Clark AM, Wheeler SE, Young CL, Stockdale L, Shepard Neiman J, Zhao W, Stolz DB, Venkataramanan R, Lauffenburger D, Griffith L, Wells A. A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties. Lab Chip. 2016 Dec 20;17(1):156-168. PubMed PMID: 27910972; PubMed Central PMCID: PMC5242229.
341. Shehu AI, Ma X, Venkataramanan R. Mechanisms of Drug-Induced Hepatotoxicity. Clin Liver Dis. 2017 Feb;21(1):35-54. doi: 10.1016/j.cld.2016.08.002. Review. PubMed PMID: 27842774.
342. Ganesh S, Almazroo OA, Tevar A, Humar A, Venkataramanan R. Drug Metabolism, Drug Interactions, and Drug-Induced Liver Injury in Living Donor Liver Transplant Patients. Clin Liver Dis. 2017 Feb;21(1):181-196. doi: 10.1016/j.cld.2016.08.011. Review. PubMed PMID: 27842771.
343. Almazroo OA, Miah MK, Venkataramanan R. Drug Metabolism in the Liver. Clin Liver Dis. 2017 Feb;21(1):1-20. doi: 10.1016/j.cld.2016.08.001. Epub 2016 Oct 15. Review. PubMed PMID: 27842765.
344. Chen Y, Xia R, Huang Y, Zhao W, Li J, Zhang X, Wang P, Venkataramanan R, Fan J, Xie W, Ma X, Lu B, Li S. An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy. Nat Commun. 2016 Nov 7; 7:13443. doi: 10.1038/ncomms13443. PubMed PMID: 27819653; PubMed Central PMCID: PMC5103075.
345. Bustos ML, Zhao Y, Chen H, Caritis SN, Venkataramanan R. Polymorphisms in CYP1A1 and CYP3A5 Genes Contribute to the Variability in Granisetron Clearance and Exposure in Pregnant Women with Nausea and Vomiting. Pharmacotherapy. 2016 Dec;36(12):1238-1244. doi: 10.1002/phar.1860. Epub 2016 Dec 5. PubMed PMID: 27809336.
346. Bastian JR, Chen H, Zhang H, Rothenberger S, Tarter R, English D, Venkataramanan R, Caritis SN. Dose-adjusted plasma concentrations of sublingual buprenorphine are lower during than after pregnancy. Am J Obstet Gynecol. 2017 Jan;216(1):64. e1-64. e7. doi: 10.1016/j.ajog.2016.09.095. Epub 2016 Sep 26. PubMed PMID: 27687214; PubMed Central PMCID: PMC5245872.
347. Siminerio L, Venkataramanan R, Caritis S. Selective serotonin reuptake inhibitors and childhood motor skill impairment-what can be concluded? BJOG. 2016 Nov;123(12):1918. doi: 10.1111/1471-0528.13581. Epub 2015 Sep 15. PubMed PMID: 26374134; PubMed Central PMCID: PMC4811734.
348. Sun J, Chen Y, Li K, Huang Y, Fu X, Zhang X, Zhao W, Wei Y, Xu L, Zhang P, Venkataramanan R, Li S. A prodrug micellar carrier assembled from polymers with pendant farnesyl thiosalicylic acid moieties for improved delivery of paclitaxel. Acta Biomater. 2016 Oct 1; 43:282-91. doi: 10.1016/j.actbio.2016.07.014. Epub 2016 Jul 12. PubMed PMID: 27422196; PubMed Central PMCID: PMC5012958.
349. Kalluri HV, Zhang H, Caritis SN, Venkataramanan R. A physiologically basedpharmacokinetic modelling approach to predict buprenorphine pharmacokinetics following intravenous and sublingual administration. Br J Clin Pharmacol. 2017 Nov;83(11):2458-2473. doi: 10.1111/bcp.13368. Epub 2017 Aug 22. PubMed PMID: 28688108; PubMed Central PMCID: PMC5651326.
350. Caritis SN, Bastian JR, Zhang H, Kalluri H, English D, England M, Bobby S, Venkataramanan R. An evidence-based recommendation to increase the dosing frequency of buprenorphine during pregnancy. Am J Obstet Gynecol. 2017 Oct;217(4): 459.e1-459.e6. doi: 10.1016/j.ajog.2017.06.029. Epub 2017 Jun 29. PubMed PMID: 28669739; PubMed Central PMCID: PMC5614874.
351. Rivosecchi RM, Clancy CJ, Shields RK, Ensor CR, Shullo MA, Falcione BA, Venkataramanan R, Nguyen MH. Effects of Isavuconazole on the Plasma Concentrations of Tacrolimus among Solid-Organ Transplant Patients. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00970-17. doi: 10.1128/AAC.00970-17 Print 2017 Sep. PubMed PMID: 28674051; PubMed Central PMCID: PMC5571345.
352. Sindhi R, Higgs BW, Venkataramanan R, Moritz ML. Synergistic immunosuppressionand unintended consequences. Pediatr Transplant. 2017 Nov;21(7). doi: 10.1111/petr.13047. Epub 2017 Aug 21. PubMed PMID: 28833989.
353. Caritis SN, Hankins G, Hebert M, Haas DM, Ahmed M, Simhan H, Haneline LA, Harris J, Chang J, Famy AS, Yorio P, Ren Z, D'Alton ME, Venkataramanan R. Impact of Pregnancy History and 17-Hydroxyprogesterone Caproate on Cervical Cytokines and Matrix Metalloproteinases. Am J Perinatol. 2018 Apr;35(5):470-480. doi: 10.1055/s-0037-1608631. Epub 2017 Nov 15. PubMed PMID: 29141262; PubMed Central PMCID: PMC5876094.
354. Hoberman A, Paradise JL, Rockette HE, Jeong JH, Kearney DH, Bhatnagar S, Shope TR, Muñiz G, Martin JM, Kurs-Lasky M, Haralam M, Pope MA, Nagg JP, Zhao W, Miah MK, Beumer J, Venkataramanan R, Shaikh N. Erratum for Hoberman et al., "Reduced-Concentration Clavulanate for Young Children with Acute Otitis Media". Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e02110-17. doi: 10.1128/AAC.02110-17. Print 2018 Jan. PubMed PMID: 29269433; PubMed Central PMCID: PMC5740386.
355. Wang P, Shehu AI, Lu J, Joshi RH, Venkataramanan R, Sugamori KS, Grant DM, Zhong XB, Ma X. Deficiency of N-acetyltransferase increases the interactions of isoniazid with endobiotics in mouse liver. Biochem Pharmacol. 2017 Dec 1; 145:218-225. doi: 10.1016/j.bcp.2017.09.001. Epub 2017 Sep 6. PubMed PMID: 28888949; PubMed Central PMCID: PMC5681379
356. van der Merwe Y, Faust AE, Conner I, Gu X, Feturi F, Zhao W, Leonard B, Roy S, Gorantla VS, Venkataramanan R, Washington KM, Wagner WR, Steketee MB. An Elastomeric Polymer Matrix, PEUU-Tac, Delivers Bioactive Tacrolimus Transdurally to the CNS in Rat. EBioMedicine. 2017 Dec; 26:47-59. doi: 10.1016/j.ebiom.2017.11.017. Epub 2017 Nov 24. PubMed PMID: 29208469; PubMed Central PMCID: PMC5832622.
357. Hauspurg A, Lemon LS, Serra AE, Sharma S, Venkataramanan R, Caritis SN. Impact of Obesity on the Rate of Recurrent Spontaneous Preterm Birth in Women Treated with 17-alpha Hydroxyprogesterone Caproate. Am J Perinatol. 2018 Jan 2. doi: 10.1055/s-0037-1617453. [Epub ahead of print] PubMed PMID: 29294501.
358. Liu L, Wheeler SE, Venkataramanan R, Rymer JA, Pizon AF, Lynch MJ, Tamama K. Newly Emerging Drugs of Abuse and Their Detection Methods: An ACLPS Critical Review. Am J Clin Pathol. 2018 Jan 29;149(2):105-116. doi: 10.1093/ajcp/aqx138. PubMed PMID: 29385414.
359. Lemon LS, Naimi A, Caritis SN, Platt RW, Venkataramanan R, Bodnar LM. The Role of Preterm Birth in the Association Between Opioid Maintenance Therapy and Neonatal Abstinence Syndrome. Paediatr Perinat Epidemiol. 2018 Mar;32(2):213-222. doi: 10.1111/ppe.12443. Epub 2018 Jan 26. PubMed PMID: 29372750; PubMed Central PMCID: PMC5902412.
360. Lemon LS, Caritis SN, Venkataramanan R, Platt RW, Bodnar LM. Methadone Versus Buprenorphine for Opioid Use Dependence and Risk of Neonatal Abstinence Syndrome. Epidemiology. 2018 Mar;29(2):261-268. doi: 10.1097/EDE.0000000000000780. PubMed PMID: 29112519; PubMed Central PMCID: PMC5792296.
361. Clark AM, Kumar MP, Wheeler SE, Young CL, Venkataramanan R, Stolz DB, Griffith LG, Lauffenburger DA, Wells A. A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures. Mol Cell Proteomics. 2018 Apr;17(4):619-630. doi: 10.1074/mcp. RA117.000370. Epub 2018 Jan 20. PubMed PMID: 29353230; PubMed Central PMCID: PMC5880110.
362. Ensor CR, Iasella CJ, Harrigan KM, Morrell MR, Moore CA, Shigemura N, Zeevi A, McDyer JF, Venkataramanan R. Increasing tacrolimus time-in-therapeutic range is associated with superior one-year outcomes in lung transplant recipients. Am J Transplant. 2018 Jun;18(6):1527-1533. doi: 10.1111/ajt.14723. Epub 2018 Apr 6. PubMed PMID: 29513387.
363. Ryu RJ, Easterling TR, Caritis SN, Venkataramanan R, Umans JG, Ahmed MS, Clark S, Kantrowitz-Gordon I, Hays K, Bennett B, Honaker MT, Thummel KE, Shen DD, Hebert MF. Prednisone Pharmacokinetics During Pregnancy and Lactation. J Clin Pharmacol. 2018 Sep;58(9):1223-1232. doi: 10.1002/jcph.1122. Epub 2018 May 7. PubMed PMID: 29733485; PubMed Central PMCID: PMC6310475.
364. Feturi FG, Weinstock M, Zhao W, Zhang W, Schnider JT, Erbas VE, Oksuz S, Plock JA, Rohan L, Spiess AM, Ferreira LM, Solari MG, Venkataramanan R, Gorantla VS. Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokinetics. Front Surg. 2018 May 9; 5:20. doi: 10.3389/fsurg.2018.00020. eCollection 2018. PubMed PMID: 29868602; PubMed CentralPMCID: PMC5954844.
365. Zhang H, Kalluri HV, Bastian JR, Chen H, Alshabi A, Caritis SN, Venkataramanan R. Gestational changes in buprenorphine exposure: A physiologically based pharmacokinetic analysis. Br J Clin Pharmacol. 2018 Sep;84(9):2075-2087. doi: 10.1111/bcp.13642. Epub 2018 Jun 21. PubMed PMID: 29873094; PubMed Central PMCID: PMC6089832.
366. Sin SH, Eason AB, Bigi R, Kim Y, Kang S, Tan K, Seltzer TA, Venkataramanan R, An H, Dittmer DP. Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections. J Virol. 2018 Sep 12;92(19). pii: e01138-18. doi: 10.1128/JVI.01138-18. Print 2018 Oct 1. PubMed PMID: 30021906; PubMed Central PMCID: PMC6146794.
367. Ensor CR, Goehring KC, Iasella CJ, Moore CA, Lendermon EA, McDyer JF, Morrell MR, Sciortino CM, Venkataramanan R, Wiland AM. Belatacept for maintenance immunosuppression in cardiothoracic transplantation: The potential frontier. Clin Transplant. 2018 Oct;32(10): e13363. doi: 10.1111/ctr.13363. Epub 2018 Sep 10. Review. PubMed PMID: 30058177.
368. Caritis SN, Hauspurg A, Venkataramanan R, Lemon L. Defining the clinical response to 17-alpha hydroxyprogesterone caproate. Am J Obstet Gynecol. 2018 Dec;219(6):623-625. doi: 10.1016/j.ajog.2018.08.040. Epub 2018 Aug 29. PubMed PMID: 30171841.
369. Xu J, Zhao W, Sun J, Huang Y, Wang P, Venkataramanan R, Yang D, Ma X, Rana A, Li S. Novel glucosylceramide synthase inhibitor based prodrug copolymer micelles for delivery of anticancer agents. J Control Release. 2018 Oct 28; 288:212-226. doi: 10.1016/j.jconrel.2018.09.011. Epub 2018 Sep 14. PubMed PMID: 30223045; PubMed Central PMCID: PMC6177216.
370. Wu X, Clancy CJ, Rivosecchi RM, Zhao W, Shields RK, Marini RV, Venkataramanan R, Nguyen MH. Pharmacokinetics of Intravenous Isavuconazole in Solid-Organ Transplant Recipients. Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e01643-18. doi: 10.1128/AAC.01643-18. Print 2018 Dec. PubMed PMID: 30275091; PubMed Central PMCID: PMC6256763.
371. Shah M, Xu M, Shah P, Wang X, Clark SM, Costantine M, West HA, Nanovskaya TN, Ahmed MS, Abdel-Rahman SZ, Venkataramanan R, Caritis SN, Hankins GDV, Rytting E. Effect of CYP2C9 Polymorphisms on the Pharmacokinetics of Indomethacin During Pregnancy. Eur J Drug Metab Pharmacokinet. 2019 Feb;44(1):83-89. doi: 10.1007/s13318-018-0505-7. PubMed PMID: 30159654; PubMed Central PMCID: PMC6380929.
372. Hauspurg A, Lemon L, Venkataramanan R, Caritis SN. Reply. Am J Obstet Gynecol. 2019 Feb 18. pii: S0002-9378(19)30383-7. doi: 10.1016/j.ajog.2019.02.031. [Epub ahead of print] PubMed PMID: 30790567.
373. Elens L, Langman LJ, Hesselink DA, Bergan S, Moes DJAR, Molinaro M, Venkaramanan R, Lemaitre F. Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug-Drug Interactions. Ther Drug Monit. 2020 Jun;42(3):360-368. doi:10.1097/FTD.0000000000000761. PMID: 32304488; PMCID: PMC7188032.
374. Hauspurg A, Lemon L, Venkataramanan R, Caritis SN. Reply. Am J Obste Gynecol. 2019 Jun;220(6):608-609. doi: 10.1016/j.ajog.2019.02.031. Epub 2019 Feb 18. PMID: 30790567.
375. Liao MZ, Flood Nichols SK, Ahmed M, Clark S, Hankins GD, Caritis S, Venkataramanan R, Haas D, Quinney SK, Haneline LS, Tita AT, Manuck T, Wang J, Thummel KE, Brown LM, Ren Z, Easterling TR, Hebert MF. Effects of Pregnancy on The pharmacokinetics of Metformin. Drug Metab Dispos. 2020 Apr;48(4): 264-271.doi: 10.1124/dmd.119.088435. Epub 2020 Jan 24. PMID: 31980499; PMCID: PMC7076518.
376. Lemon LS, Bodnar LM, Garrard W, Venkataramanan R, Platt RW, Marroquin OC, Caritis SN. Ondansetron use in the first trimester of pregnancy and the risk of neonatal ventricular septal defect. Int J Epidemiol. 2020 Apr 1;49(2):648-656. doi:10.1093/ije/dyz255. PMID: 31860078; PMCID: PMC7266534.
377. Caritis SN, Venkataramanan R. Naltrexone use in pregnancy: a time for change. Am J Obstet Gynecol. 2020 Jan;222(1):1-2. doi: 10.1016/j.ajog.2019.08.041. PMID: 31883574.
378. Shuster DL, Shireman LM, Ma X, Shen DD, Flood Nichols SK, Ahmed MS, Clark S, Caritis S, Venkataramanan R, Haas DM, Quinney SK, Haneline LS, Tita AT, Manuck TA, Thummel KE, Brown LM, Ren Z, Brown Z, Easterling TR, Hebert MF. Pharmacodynamics of Glyburide, Metformin, and Glyburide/Metformin Combination Therapy in the Treatment of Gestational Diabetes Mellitus. Clin Pharmacol Ther. 2020 Jun;107(6):1362-1372. doi: 10.1002/cpt.1749. Epub 2020 Jan 25. PMID: 31869430; PMCID: PMC7561209.
379. Chaphekar N, Caritis S, Venkataramanan R. Model-Informed Dose Optimization in Pregnancy. J Clin Pharmacol. 2020 Oct;60 Suppl 1: S63-S76. doi: 10.1002/jcph.1777. PMID: 33205432.
380. Zhang H, Bastian JR, Zhao W, Chen H, Shaik IH, Chaphekar N, Caritis SN, Venkataramanan R. Pregnancy Alters CYP- and UGT-Mediated Metabolism of Buprenorphine. Ther Drug Monit. 2020 Apr;42(2):264-270. doi: 10.1097/FTD.0000000000000724. PMID: 31929398.
381. Wu X, Venkataramanan R, Rivosecchi RM, Tang C, Marini RV, Shields RK, Clancy CJ, Nguyen MH. Population Pharmacokinetics of Intravenous Isavuconazole in Solid-Organ Transplant Recipients. Antimicrob Agents Chemother. 2020 Jan 27;64(2): e01728-19. doi: 10.1128/AAC.01728-19. PMID: 31767725; PMCID: PMC6985716.
382. Shah M, Xu M, Shah P, Wang X, Clark SM, Costantine M, West HA, Nanovskaya TN, Ahmed MS, Abdel-Rahman SZ, Venkataramanan R, Caritis SN, Hankins GDV, Rytting E. Effect of CYP2C9 Polymorphisms on the Pharmacokinetics of Indomethacin During Pregnancy. Eur J Drug Metab Pharmacokinet. 2019 Feb;44(1):83-89. doi: 10.1007/s13318-018-0505-7. PMID: 30159654; PMCID: PMC6380929.
383. Joshi A, Guo J, Holleran JL, Kiesel B, Taylor S, Christner S, Parise RA, Miller BM, Ivy SP, Chu E, Venkataramanan R, Beumer JH. Evaluation of the pharmacokinetic drug-drug interaction potential of iohexol, a renal filtration marker. Cancer Chemother Pharmacol. 2020 Oct;86(4):535-545. doi: 0.1007/s00280-020-04145-6. Epub 2020 Sep 18. PMID: 32948918; PMCID: PMC7521612.
384. Joshi A, Kiesel BF, Chaphekar N, Jones R, Guo J, Kunos CA, Taylor S, Chu E, Venkataramanan R, Beumer JH. In vitro evaluation of the metabolic enzymes and drug interaction potential of triapine. Cancer Chemother Pharmacol. 2020 Nov;86(5):633-640. doi: 10.1007/s00280-020-04154-5. Epub 2020 Sep 28. PMID:
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385. Feturi FG, Schnider JT, Fanzio PM, Erbas VE, Oksuz S, Sahin H, Dong L, Unadkat JM, Spiess AM, Plock JA, Solari MG, Gorantla VS, Venkataramanan R. Pharmacokinetics and Biodistribution of Tacrolimus after Topical Administration: Implications for Vascularized Composite Allotransplantation. Pharm Res. 2020 Oct
16;37(11):222. doi: 10.1007/s11095-020-02921-w. PMID: 33067715.
386. Wu X, Zhang H, Miah MK, Caritis SN, Venkataramanan R. Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations. J Clin Pharmacol. 2020 Apr;60(4):477-488. doi: 10.1002/jcph.1541. Epub 2019 Nov 21. PMID: 31750550.
387. Xu J, Sun J, Ho PY, Luo Z, Ma W, Zhao W, Rathod SB, Fernandez CA, Venkataramanan R, Xie W, Yu AM, Li S. Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis.
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388. Lu J, Zhao W, Huang Y, Liu H, Marquez R, Gibbs RB, Li J, Venkataramanan R, Xu L, Li S, Li S. Correction to "Targeted Delivery of Doxorubicin by Folic Acid- Decorated Dual Functional Nanocarrier". Mol Pharm. 2019 Sep 3;16(9):4087. doi: 10.1021/acs.molpharmaceut.9b00818. Epub 2019 Aug 9. Erratum for: Mol Pharm. 2014 Nov 3;11(11):4164-78. PMID: 31397164.
389. Shuster DL, Shireman LM, Ma X, Shen DD, Flood Nichols SK, Ahmed MS, Clark S, Caritis S, Venkataramanan R, Haas DM, Quinney SK, Haneline LS, Tita AT, Manuck TA, Thummel KE, Morris Brown L, Ren Z, Brown Z, Easterling TR, Hebert MF. Pharmacodynamics of Metformin in Pregnant Women With Gestational Diabetes Mellitus and Nonpregnant Women With Type 2 Diabetes Mellitus. J Clin Pharmacol. 2020 Apr;60(4):540-549. doi: 10.1002/jcph.1549. Epub 2019 Nov 19. PMID: 31742716; PMCID: PMC7064374.
390. Kalluri HV, Sood P, Zhao W, Randhawa PS, Tevar AD, Hariharan S, Humar A, Venkataramanan R. Evaluation of Renal Anionic Secretion Following Living-donor and Deceased-donor Renal Transplantation: A Clinical Pharmacokinetic Study of Cefoxitin Microdosing. Transplant Direct. 2020 May 28;6(6): e561. doi: 10.1097/TXD.0000000000001001. PMID: 33062845; PMCID: PMC7531749.
391. Thanukrishnan H, Corcoran TE, Iasella CJ, Moore CA, Nero JA, Morrell MR, McDyer JF, Hussain S, Nguyen MH, Venkataramanan R, Ensor CR. Aerosolization of Second-generation Triazoles: In Vitro Evaluation and Application in Therapy of Invasive Airway Aspergillosis. Transplantation. 2019 Dec;103(12):2608-2613. doi: 10.1097/TP.0000000000002697. PMID: 31343565.
392. Santiago D, Mangas-Sanjuan V, Melin K, Duconge J, Zhao W, Venkataramanan R. Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder in Puerto Rico. Pharmaceutics. 2020 Dec 18;12(12):1226. doi: 10.3390/pharmaceutics12121226. PMID: 33352843; PMCID: PMC7766849.
393. Lemaitre F, Vethe NT, D'Avolio A, Tron C, Robertsen I, De Winter B, Denicolo A, Koch BCP, Venkataramanan R, Van Gelder T, Brunet M, Bergan S, Hesselink DA, Wallemacq P. Measuring Intracellular Concentrations of Calcineurin Inhibitors: Expert Consensus from the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Expert Panel. Ther Drug Monit. 2020 Oct;42(5):665-670. doi: 10.1097/FTD.0000000000000780. PMID: 32520841.
394. Almazroo OA, Miah MK, Pillai VC, Shaik IH, Xu R, Dharmayan S, Johnson HJ, Ganesh S, Planinsic RM, Demetris AJ, Al-Khafaji A, Lopez R, Molinari M, Tevar AD, Hughes C, Humar A, Venkataramanan R. An evaluation of the safety and preliminary efficacy of peri- and post-operative treprostinil in preventing ischemia and reperfusion injury in adult orthotopic liver transplant recipients. Clin Transplant. 2021 Jun;35(6):e14298. doi: 10.1111/ctr.14298. Epub 2021 May 5. PMID: 33764591; PMCID: PMC8243925.
395. Bergan S, Brunet M, Hesselink DA, Johnson-Davis KL, Kunicki PK, Lemaitre F, Marquet P, Molinaro M, Noceti O, Pattanaik S, Pawinski T, Seger C, Shipkova M, Swen JJ, van Gelder T, Venkataramanan R, Wieland E, Woillard JB, Zwart TC, Barten MJ, Budde K, Dieterlen MT, Elens L, Haufroid V, Masuda S, Millan O, Mizuno T, Moes DJAR, Oellerich M, Picard N, Salzmann L, Tönshoff B, van Schaik RHN, Vethe NT, Vinks AA, Wallemacq P, Åsberg A, Langman LJ. Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Ther Drug Monit. 2021 Apr 1;43(2):150-200. doi: 10.1097/FTD.0000000000000871. PMID: 33711005.
396. Huang H, Xie H, Chaphekar N, Xu R, Venkataramanan R, Wu X. A physiologically based pharmacokinetic analysis to predict the pharmacokinetics of intravenous isavuconazole in patients with or without hepatic impairment. Antimicrob Agents Chemother. 2021 Feb 22;65(5): e02032-20. doi: 10.1128/AAC.02032-20. Epub ahead of print. PMID: 33619060; PMCID: PMC8092901.
397. Coons JC, Crisamore K, Adams S, Modany A, Simon MA, Zhao W, Shaik IH, Venkataramanan R, Empey PE. A pilot study of oral treprostinil pharmacogenomics and treatment persistence in patients with pulmonary arterial hypertension. Ther Adv Respir Dis. 2021 April (Jan-Dec); 15:17534666211013688. doi: 10.1177/17534666211013688. PMID: 33929912; PMCID: PMC8111525.
398. Pilch NA, Sell ML, McGhee W. Venkataramanan R. Important considerations for drugs, nutritional, and herbal supplements in pediatric solid organ transplant recipients. Pediatr Transplant. 2021 Feb;25(1): e13881. doi: 10.1111/petr.13881. Epub 2020 Nov 3. PMID: 33142023.
399. Megli CJ, Hauspurg A, Venkataramanan R, Caritis SN. A Possible Mechanism of Action of 17α-Hydroxyprogesterone Caproate: Enhanced IL-10 Production. Am J Perinatol. 2023 Oct;40(14):1585-1589. doi: 10.1055/s-0041-1739354. Epub 2021 Nov 16. PMID: 34784615; PMCID: PMC9879021.
400. Pillai VC, Shah M, Rytting E, Nanovskaya TN, Wang X, Clark SM, Ahmed MS, Hankins GDV, Caritis SN, Venkataramanan R. Prediction of maternal and fetal pharmacokinetics of indomethacin in pregnancy. Br J Clin Pharmacol. 2022 Jan;88(1):271-281. doi: 10.1111/bcp.14960. Epub 2021 Jul 22. PMID: 34185331
401. Wu X, Zhang X, Xu R, Shaik IH, Venkataramanan R. Physiologically based pharmacokinetic modelling of treprostinil after intravenous injection and extended-release oral tablet administration in healthy volunteers: An extrapolation to other patient populations including patients with hepatic impairment. Br J Clin Pharmacol. 2022 Feb;88(2):587-599. doi: 10.1111/bcp.14966. Epub 2021 Jul 23. PMID: 34190364; PMCID: PMC9290939.
402. Santiago D, Rosario Y, Melin K, Duconge J, Roman L, Gonzalez A, Venkataramanan R. Brand-to-generic substitution of buprenorphine/naloxone sublingual film in Puerto Rico: A case study. P R Health Sci J. 2021 Dec;40(4):192-194.PMID: 35077080
403. Jain A, Wu R, Venkataramanan R et al. Belatacept exposure is altered with plasmaphoresis. Transplantation. Transplantation. 2021 Oct 1;105(10): e152-e153. doi: 10.1097/TP.0000000000003840.PMID: 34591818
404. Caritis SN, Venkataramanan R. Obstetrical, fetal, and lactation pharmacology-a crisis that can no longer be ignored. Am J Obstet Gynecol. 2021 Jul;225(1):10-20. doi: 10.1016/j.ajog.2021.02.002. PMID: 34215351.
405. Costantine MM, West H, Wisner KL, Caritis S, Clark S, Venkataramanan R, Stika CS, Rytting E, Wang X, Ahmed MS; Eunice Kennedy Shriver National Institute of Child Health and Human Development Obstetric-Fetal Pharmacology Research Centers (OPRC) Network, Bethesda, MD. A randomized pilot clinical trial of pravastatin versus placebo in pregnant patients at high risk of preeclampsia. Am J Obstet Gynecol. 2021 Dec;225(6):666.e1-666.e15. doi: 10.1016/j.ajog.2021.05.018. Epub 2021 May 24. PMID: 34033812
406. Chaphekar N, Caritis S, Venkataramanan Maternal Fetal Pharmacology. Front Pediatr. 2021 Nov 3; 9:733823. doi: 10.3389/fped.2021.733823. PMID: 34805038; PMCID: PMC8596611.
407. Kiesel BF, Guo J, Parise RA, Venkataramanan R, Clump DA, Bakkenist CJ, Beumer JH. Dose-dependent bioavailability and tissue distribution of the ATR inhibitor AZD6738 (ceralasertib) in mice. Cancer Chemother Pharmacol. 2022 Feb;89(2):231-242. doi: 10.1007/s00280-021-04388-x. Epub 2022 Jan 23. PMID: 35066692; PMCID: PMC8829872.
408. Feturi FG, Unadkat JV, Zhang W, Hag ME, Wang Y, Komatsu C, Grybowski D, Zhang Z, Erbas V, Sahin H, Mcclaine S, Oksuz S, Plock J, Gorantla VS, Washington KM, Solari MG, Venkataramanan R, Spiess AM. Tacrolimus-Eluting Disk within the Allograft Enables Vascularized Composite Allograft Survival with Site-Specific Immunosuppression without Systemic Toxicity. Pharm Res. 2022 Sep;39(9):2179-2190. doi: 10.1007/s11095-022-03345-4. Epub 2022 Aug 2. PMID: 35915321.
409. Lemaitre F, Budde K, Van Gelder T, Bergan S, Lawson R, Noceti O, Venkataramanan R, Elens L, Moes DJAR, Hesselink DA, Pawinski T, Johnson-Davis KL, De Winter BCM, Pattanaik S, Brunet M, Masuda S, Langman LJ. Therapeutic Drug Monitoring and Dosage Adjustments of Immunosuppressive Drugs When Combined With Nirmatrelvir/Ritonavir in Patients With COVID-19. Ther Drug Monit. 2023 Apr 1;45(2):191-199. doi: 10.1097/FTD.0000000000001014. PMID: 35944126.
410. Megli C, Combs CA, Venkataramanan R, Lemon L, Caritis SN. Recurrent Preterm Birth Reduction by 17-Hydroxyprogesterone Caproate in Dichorionic/Diamniotic Twin Gestation. Am J Perinatol. 2022 Aug;39(11):1183-1188. doi: 10.1055/s-0040-1721713. Epub 2020 Dec 15. PMID: 33321529.
411. Gramignoli R, Ranade AR, Venkataramanan R, Strom SC. Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes. Int J Mol Sci. 2022 Nov 28;23(23):14880. doi: 10.3390/ijms232314880. PMID: 36499207; PMCID: PMC9740548.
412. Stika CS, Wisner KL, George AL Jr, Avram MJ, Zumpf K, Rasmussen-Torvik LJ, Mesches GA, Caritis SN, Venkataramanan R, Costantine MM, West HA, Clark S, Ciolino JD. Changes in Sertraline Plasma Concentrations Across Pregnancy and Postpartum. Clin Pharmacol Ther. 2022 Dec;112(6):1280-1290. doi: 10.1002/cpt.2746. Epub 2022 Oct 6. PMID: 36094046.
413. Almazroon O, Shaik I, Venkataramanan R. Treprostinil supplementation ameliorates hepatic ischemia reperfusion injury and regulates hepatic transporter expression: An isolated perfused rat liver study. submitted to Pharmaceutical Research Pharm Res. 2022 Nov;39(11):2979-2990. doi: 10.1007/s11095-022-03384-x. Epub 2022 Sep 7. PMID: 36071353; PMCID: PMC9633539.
414. Thanukrishnan H, Venkataramanan R, Mehta RB, Jorgensen D, Sood P. The combination of exposure to Tacrolimus, mycophenolic acid, Inosine 5'-Monophosphate Dehydrogenase activity and inhibition in the first week define early histological outcomes in renal transplant recipients. Clin Transplant. 2022 Dec;36(12):e14830. doi: 10.1111/ctr.14830. Epub 2022 Oct 26. PMID: 36177865.
415. Mesches GA, Ciolino JD, Stika CS, Sit DK, Zumpf K, Fisher S, Clark CT, George AL, Avram MJ, Rasmussen-Torvik LJ, Erickson DL, Caritis S, Fischer D, Venkataramanan R, Costantine M, West H, Welch E, Clark S, Wisner KL, Gollan JK. Trajectories of Depressive and Anxiety Symptoms Across Pregnancy and Postpartum in Selective Serotonin Reuptake Inhibitor-Treated Women. Psychiatr Res Clin Pract. 2022 Mar 4;4(2):32-41. doi: 10.1176/appi.prcp.20210034. PMID: 36254188; PMCID: PMC9558923.
416. Hansen-Estruch C, Bikhet MH, Javed M, Katsurada A, Satou R, Shao W, Ayares D, Venkataramanan R, Cooper DKC, Judd E, Navar LG. Renin-angiotensin-aldosterone system function in the pig-to-baboon kidney xenotransplantation model. Am J Transplant. 2023 Jan 5: S1600-6135(22)29293-4. doi: 10.1016/j.ajt.2022.11.022. Epub ahead of print. PMID: 36695679.
417. Dodeja P, Giannoutsos S, Caritis S, Venkataramanan R. Applications of Volumetric Absorptive Microsampling Technique: A Systematic Critical Review. Ther Drug Monit. 2023 Mar 6. doi: 10.1097/FTD.0000000000001083. Epub ahead of print. PMID: 36917733.
418. Hansen-Estruch C, Bikhet MH, Shaik IH, Vasudevan V, Zhao W, Javed M, Collins DE, Ayares D, Judd E, Cooper DKC, Venkataramanan R. Assessment of glomerular filtration and tubular secretion in baboons with life-supporting pig kidney grafts. Xenotransplantation. 2023 Mar;30(2):e12795. doi: 10.1111/xen.12795. Epub 2023 Feb 23. PMID: 36820525; PMCID: PMC10354795.
419. Bank TC, Stika CS, Venkataramanan R, Field C, Costantine MM. Challenges in Conducting Therapeutic Trials in Pregnancy: Emphasizing Recent Lessons Learned. J Clin Pharmacol. 2023 Jun;63 Suppl 1:S117-S125. doi: 10.1002/jcph.2226. PMID: 37317490.
420. Alshabi A, Shaik IH, Zhao Y, Pillai VC, Caritis S, Venkataramanan R. A cocktail probe approach to evaluate the effect of hormones on the expression and activity of CYP enzymes in human hepatocytes with conditions simulating late stage of pregnancy. Eur J Clin Pharmacol. 2023 Jun;79(6):815-827. doi: 10.1007/s00228-023-03489-1. Epub 2023 Apr 15. PMID: 37060457; PMCID: PMC10105140.
421. Huang H, Xie H, Chaphekar N, Xu R, Venkataramanan R, Wu X. A physiologically based pharmacokinetic analysis to predict the pharmacokinetics of intravenous isavuconazole in patients with or without hepatic impairment. Antimicrob Agents Chemother. 2023 May 1;65(5):e02032-20. doi: 10.1128/AAC.02032-20. Epub 2021 Feb 22. PMID: 33619060; PMCID: PMC8092901.
422. Shaik IH, Chaphekar N, Vasudevan V, Alshabi A, Bastian JR, Zhao W, Caritis S, Venkataramanan R. Effect of formulation and route of administration on the distribution of 17-hydroxyprogesterone caproate in rats. Xenobiotica. 2023 Mar;53(3):193-200. doi: 10.1080/00498254.2023.2201348. Epub 2023 Apr 20. PMID: 37039113
423. Yoshida S, Kreger AM, Shaik IH, West RE 3rd, Venkataramanan R, Gittes GK. Intra-amniotic sildenafil administration in rabbits: Safety, pharmacokinetics, organ distribution and histologic evaluation. Toxicol Appl Pharmacol. 2023 Jun 15;469:116527. doi: 10.1016/j.taap.2023.116527. Epub 2023 Apr 18. PMID: 37080362.
424. Firuz G. Feturi,1 Vasil E. Erbas,2 Zhaoxiang Zhang,3 Lewei Dong,3 Huseyin Sahin,4 Jonas T. Schnider,3 Yang Li,3 Sinan Oksuz,5 Wensheng Zhang,3 Sean Mcclaine,3 Jan Niec,3 Jan Plock,6 Jignesh V. Unadkat,3 Kia M. Washington,3,7 Alexander M. Spiess,3 Mario G. Solari,3 Vijay S. Gorantla,8 Raman Venkataramanan,1,9 Topical Immunotherapy Synergizes with Low Systemic Immunotherapy to Prolong Survival of Vascularized Composite Allografts without Systemic Adverse Effects (J Pharm Sci – In Press)
425. Caritis SN, Costantine MM, Clark S, Stika CS, Kiley JW, Metz TD, Chauhan SP, Venkataramanan R; Eunice Kennedy Shriver National Institute of Child Health and Human Development Obstetric-Fetal Pharmacology Research Centers Network. Relationship between plasma concentration of 17-hydroxyprogesterone caproate and gestational age at preterm delivery. Am J Obstet Gynecol MFM. 2023 Apr 24;5(7):100980. doi: 10.1016/j.ajogmf.2023.100980. PMID: 37100349; PMCID: PMC10330330
426. Alshogran OY, Dodeja P, Albukhaytan H, Laffey T, Chaphekar N, Caritis S, Shaik IH, Venkataramanan R. Drugs in Human Milk Part 1: Practical and Analytical Considerations in Measuring Drugs and Metabolites in Human Milk. Clin Pharmacokinet. 2024 May;63(5):561-588. doi: 10.1007/s40262-024-01374-3. Epub 2024 May 15. PMID: 38748090
427. Caritis SN, Dodeja P, Sharma S, Zhao W, Venkataramanan R. The dosing regimen for 17-hydroxyprogesterone caproate was suboptimal: lessons for future pharmacotherapy for pregnant women. Am J Obstet Gynecol. 2024 Apr 25:S0002-9378(24)00526-X. doi: 10.1016/j.ajog.2024.04.020. Epub ahead of print. PMID: 38670444.
428. Nilkant R, Kathiresan C, Kumar N, Caritis S, Shaik IH, Venkataramanan R. Selection of a Suitable Animal Model to Evaluate Secretion of Drugs in the Human Milk: A Systematic Approach. Xenobiotica. 2024 Apr 18:1-23. doi: 10.1080/00498254.2024.2345283. Epub ahead of print. PMID: 38634455.
429. Kotton CN, Kamar N, Wojciechowski D, Eder M, Hopfer H, Randhawa P, Sester M, Comoli P, Tedesco Silva H, Knoll G, Brennan DC, Trofe-Clark J, Pape L, Axelrod D, Kiberd B, Wong G, Hirsch HH; Transplantation Society International BK Polyomavirus Consensus Group. The Second International Consensus Guidelines on the Management of BK Polyomavirus in Kidney Transplantation. Transplantation. 2024 Apr 12. doi: 10.1097/TP.0000000000004976. Epub ahead of print. PMID: 38605438.
430. Zhao W, Alshogran OY, Zhang H, Joshi A, Krans EE, Caritis S, Shaik IH, Venkataramanan R. Simplified processing and rapid quantification of buprenorphine, norbuprenorphine, and their conjugated metabolites in human plasma using UPLC-MS/MS: Assessment of buprenorphine exposure during opioid use disorder treatment. J Mass Spectrom. 2024 Apr;59(4):e5015. doi: 10.1002/jms.5015. PMID: 38501738.
431. Borda LA, Någård M, Boulton DW, Venkataramanan R, Coppola P. A systematic review of pregnancy-related clinical intervention of drug regimens due to pharmacokinetic reasons. Front Med (Lausanne). 2023 Nov 29;10:1241456. doi: 10.3389/fmed.2023.1241456. PMID: 38093976; PMCID: PMC10716708
432. Xiao B, Feturi F, Su AA, Van der Merwe Y, Barnett JM, Jabbari K, Khatter NJ, Li B, Katzel EB, Venkataramanan R, Solari MG, Wagner WR, Steketee MB, Simons DJ, Washington KM. Nerve Wrap for Local Delivery of FK506/Tacrolimus Accelerates Nerve Regeneration. Int J Mol Sci. 2024 Jan 10;25(2):847. doi: 10.3390/ijms25020847. PMID: 38255920; PMCID: PMC10815243
433. Shahane A, Zhao W, Pakalapati N, Alshogran OY, Caritis SN, Lim G, Shaik IH, Venkataramanan R. Simultaneous quantitation of ketamine, norketamine and dehydronorketamine in human milk using a novel ultra high-performance liquid chromatography-mass spectrometry (UPLC-MS/MS) assay. J Pharm Biomed Anal. 2023 Sep 20;234:115502. doi: 10.1016/j.jpba.2023.115502. Epub 2023 Jun 1. PMID: 37311376; PMCID: PMC10527422.
434. Caritis SN, Costantine MM, Clark S, Stika CS, Kiley JW, Metz TD, Chauhan SP, Venkataramanan R; Eunice Kennedy Shriver National Institute of Child Health and Human Development Obstetric-Fetal Pharmacology Research Centers Network. Relationship between plasma concentration of 17-hydroxyprogesterone caproate and gestational age at preterm delivery. Am J Obstet Gynecol MFM. 2023 Jul;5(7):100980. doi: 10.1016/j.ajogmf.2023.100980. Epub 2023 Apr 24. PMID: 37100349; PMCID: PMC10330330.
435. Dodeja P, Giannoutsos S, Caritis S, Venkataramanan R. Applications of Volumetric Absorptive Microsampling Technique: A Systematic Critical Review. Ther Drug Monit. 2023 Aug 1;45(4):431-462. doi: 10.1097/FTD.0000000000001083. Epub 2023 Mar 6. PMID: 36917733.
436. 12: Megli CJ, Hauspurg A, Venkataramanan R, Caritis SN. A Possible Mechanism of Action of 17α-Hydroxyprogesterone Caproate: Enhanced IL-10 Production. Am J Perinatol. 2023 Oct;40(14):1585-1589. doi: 10.1055/s-0041-1739354. Epub 2021 Nov 16. PMID: 34784615; PMCID: PMC9879021.
437. Osama Y. Alshogran, Wenchen Zhao, Elizabeth E. Krans, Steve Caritis, Imam H. Shaik, Raman Venkataramanan. A methodological approach for improving the detection and quantitation of buprenorphine and its metabolites in maternal and neonatal hair. Therapeutic drug monitoring (revised manuscript submitted).
438. Caritis S, Venkataramanan R, Change to: A pharmocologic evaluation of buprenorphine in pregnancy and the postpartum period. J. Addiction Medicine (Revised manuscript submitted).
439. Shaik IH, Chaphekar N, Vasudevan V, Alshabi A, AlOwaifeer, A, Zhao W, Caritis S, Venkataramanan R. Feasibility and Safety of Vaginal Administration of 17-alpha hydroxyprogesterone Caproate in female rats and rabbits. Xenobiotica (Under review).
440. Dodeja P, Chaphekar N, Laffey T, Albukhytan H, Caritis S, Shaik I, Venkataramanan R. Drugs in Human Milk Part 2. Clinical Study design and modeling approaches to study secretion of drugs in human milk. Clinical Pharmacokinetics (Submitted June 2024).
441. 17. Dodeja P, Chaphekar N, Caritis S, Venkataramanan R. "Optimizing drug therapy during pregnancy: a spotlight on population pharmacokinetic modelling." Expert Opinion Drug Metabolism and Toxicology” (Submitted June 2024).
442. Nupur Chaphekar, Hongfei Zhang, Victor Mangas-Sanjuan, Steve Caritis, and Raman Venkataramanan. LIMITED SAMPLING STRATEGIES USING MULTIPLE LINEAR REGRESSION AND BAYESIAN APPROACH FOR BUPRENORPHINE AREA UNDER THE CURVE PREDICTION DURING PREGNANCY AND POSTPARTUM. J. Clin. Pharmacol. (Revised version to besubmitted June 2025)
443. Firuz G. Feturi, Zi Wang, Shrina Duggal, Maria-Stephanie A Hughes, JohnPilla, Spiros Giannoutsos, Alfred L'Altrelli, Ron J Keizer, Raman Venkataramanan. Evaluation of a Model-Based Precision Dosing Platform using Bayesian Forecasting Method for Personalized Busulfan Therapy in the Adult Hematopoietic Stem Cell Transplant Population with Limited Sampling Strategy - Experience at an Academic Medical Center. In review JCP – 2024