PhD Program: Pharmacometrics & Systems Pharmacology

About the track

The Pharmacometrics and Systems Pharmacology program focuses on applying Pharmacometrics and system pharmacology techniques to facilitate the development of novel drug candidates that are less likely to fail during clinical trials and to provide a better understanding of drug mechanisms of action and therapeutic effects at the systems pharmacology level.

  • You will develop a broad knowledge of pharmacometrics and systems pharmacology to develop drug candidates that are less likely to fail during clinical trials.
  • You will develop strong computational modeling and simulation expertise from drug target fishing, to drug lead identification, to drug profile optimization.
  • You will develop strong computational expertise on pharmacokinetics (PK) and pharmacodynamics (PD) modeling and simulation.
  • You will develop skills on multiscale modeling of biological processes at the molecular, gene, organ and organism levels.
  • Your will have opportunities to study with faculty from a variety of background including computer-aided drug design, computational and systems biology/pharmacology, population PK/PD modeling, computational chemical genomics, computational biophysics, etc.
  • Candidates with programming experience, basic/intermediate knowledge in statistics and/or hands-on modeling experience are highly desired.

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This specialization is associated with the Computational Chemical Genomics Screening Center. More about this program track is here.

Faculty Associated with this Track

Curriculum

Year 1

Fall

 

Course # Title Credits
PHARM 3042/Electives Research Pract/electives 2
PHARM 3024 Pharm Sci Seminar 1
PHARM 3009 Journal Club 1
PHARM 3040 Stat Methods 1/Recitation 3
PHARM 3011 Principles of Biochem 1
PHARM 3028 Pharmacology and Therapeutics 4
PHARM 3069 Pharmacometrics 3
Spring

 

Course # Title Credits
PHARM 3042/Electives Research Pract/electives 5
PHARM 2001 Pharmaceutical Analysis 4
PHARM 3071 Foundations in Pharm Sci 4
PHARM 3025 Pharm Sci Seminar 1
Journal Club Journal Club 1

Year 2

Fall

 

Course # Title Credits
PHARM 3042/Electives Research Pract/electives 4.5
PHARM 3038 Grant Writing 1 2
PHARM 3024 Pharm Sci Seminar 1
Journal Club Journal Club 1
PHARM 3068 Systems Pharmacology 3
PHARM 5218* PK & Drug Response* 3.5*
Spring

 

Course # Title Credits
PHARM 3042/Electives Research Pract/electives 11
PHARM 3039 Grant Writing 2 2
PHARM 3025 Pharm Sci Seminar 1
Journal Club Journal Club 1

Year 3

Fall

 

Course # Title Credits
PHARM 3042/Electives Research Practicum/electives 12 to 15